MED21 and MAGEB4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		MED21	MAGEB4
Description		mediator complex subunit 21	MAGE family member B4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Mediator Complex	Nucleus Cytoplasm
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Blastocyst Development Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination Stem Cell Population Maintenance RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Dimensional psychopathology (Social) ( 29496196)
Interacting Genes		30 interacting genes: BLOC1S6 BORCS6 BRCA1 BTF3 CDK8 CDK9 ELOA ESR1 ESR2 HGS HNF4A HTT MAGEA6 MAGEB4 MED29 MIEF1 PCBD2 POLR2A SKP1 SSC5D TARBP2 TFG THRA THRB TP53 TRIM27 TRIM72 VAV2 ZNF655 ZSCAN1	41 interacting genes: AARD ACOT11 ARID3A BLOC1S1 CCDC136 CCDC14 DVL3 EEF1AKMT3 FAM136A FAM166B FERD3L FLOT2 FTSJ3 GOLGA6L2 GPATCH2 H2AP HGS IHO1 KANK2 KRT38 LZTS2 MAGEA8 MED21 MESD NEUROD4 PFDN6 PICK1 PJA1 ROCK1 RUNDC3A SH2D1B THOC1 TNR TRAK1 UQCRB USHBP1 USP25 WDR62 YWHAE ZNF341 ZRANB1
Entrez ID		9412	4115
HPRD ID		09156	02150
Ensembl ID		ENSG00000152944	ENSG00000120289
Uniprot IDs		A0A024RAW0 Q13503	O15481
PDB IDs
Enriched GO Terms of Interacting Partners?
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