TTYH2 and KDELR2

Number of citations of the paper that reports this interaction (PubMedID 28205554)
52

Data Source:
BioGRID (fluorescent resonance energy transfer)

		TTYH2	KDELR2
Description		tweety family member 2	KDEL endoplasmic reticulum protein retention receptor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Chloride Channel Complex	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cis-Golgi Network Integral Component Of Membrane Transport Vesicle COPI-coated Vesicle Membrane
	Molecular Function	Intracellular Calcium Activated Chloride Channel Activity Protein Binding Volume-sensitive Chloride Channel Activity	KDEL Sequence Binding ER Retention Sequence Binding
	Biological Process	Chloride Transport	Protein Retention In ER Lumen Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport
Pathways		Stimuli-sensing channels	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Systolic blood pressure (cigarette smoking interaction) ( 26752167)	Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Blood protein levels ( 29875488) Body mass index ( 26426971) Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 28067908) Irritable bowel syndrome ( 25248455) Lymphocyte percentage of white cells ( 32888494 27863252) Mean platelet volume ( 32888494 27863252) Monocyte count ( 29403010 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494 27863252) Red cell distribution width ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		15 interacting genes: CCND2 CDKN2B COPB1 ERBB2 FGFR4 GPR37 GRM1 IGF1R IKBKG KAT2A KDELR2 NEDD4 NF2 PDGFRA TRARG1	22 interacting genes: AKT1 BECN1 CCND2 CD44 CDK4 CDK6 CDKN2B EPHA2 ERBB2 FGFR4 GRM1 IGF1R KAT2A LATS2 MAP2K3 MET MYC NF2 PDGFRA RASSF1 STK11 TTYH2
Entrez ID		94015	11014
HPRD ID		16394	06598
Ensembl ID		ENSG00000141540	ENSG00000136240
Uniprot IDs		B4DKD1 Q8N3U8 Q9BSA4	A0A024QZT7 P33947
PDB IDs
Enriched GO Terms of Interacting Partners?
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