COX5A and COPS6

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COX5A	COPS6
Description		cytochrome c oxidase subunit 5A	COP9 signalosome subunit 6
Image
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex IV	Nucleoplasm Cytosol COP9 Signalosome Perinuclear Region Of Cytoplasm
	Molecular Function	Cytochrome-c Oxidase Activity Protein Binding Electron Transfer Activity Metal Ion Binding	Protein Binding Metallopeptidase Activity Isopeptidase Activity
	Biological Process	Mitochondrial Electron Transport, Cytochrome C To Oxygen Proton Transmembrane Transport	Protein Deneddylation
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs		Cholic Acid N-Formylmethionine
Diseases
GWAS		Caffeine consumption ( 21490707) Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Myocardial infarction ( 33532862) Neutrophil percentage of white cells ( 32888494) Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Brain morphology (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		10 interacting genes: COPS6 CYP1A1 EPM2A EXOSC8 HTRA1 KRT31 KRT40 MESD MT-CO1 SPDEF	94 interacting genes: ANXA1 ANXA7 ASH2L BFSP2 BTBD2 C1orf174 C4orf17 CASP3 CASP6 CASP7 CASP8 CCBE1 CCDC106 CDH10 CDKN1A CDKN2C CHRNB1 COPS2 COPS3 COPS4 COPS5 COPS7B COPS8 COPS9 COX17 COX5A CRELD1 CUL1 CUL5 DIS3L2 DLEU1 EDN1 EIF3E EMD EP300 ERH FAU GPS1 HMOX2 LAMA4 LPL MAP3K1 MAP7D1 MAPK1 MAPK6 MAPKAPK3 MIF MNAT1 MYCBP NEDD8 NR3C1 ORAI2 PAEP PAFAH1B3 PBX2 PDZK1IP1 PFKL PHYHIP PMF1 PRKRA PSAP PSMD11 PTEN QTRT1 RAB27A RBX1 RFC5 ROGDI RPA2 RPL15 S100A10 SAT1 SERPINA5 SERPINB9 SHANK3 SHC3 SLC2A1 SMN1 SNRPG STK40 STX5 SULT1E1 TDGF1 TK1 TP53 TP63 TRDMT1 TRIB3 USHBP1 VIM WIPI2 ZEB2 ZFHX3 ZNF24
Entrez ID		9377	10980
HPRD ID		04799	16735
Ensembl ID		ENSG00000178741	ENSG00000168090
Uniprot IDs		P20674	Q7L5N1
PDB IDs		5Z62	4D10 4D18 4QFT 4R14 4WSN 6R6H 6R7F 6R7H 6R7I
Enriched GO Terms of Interacting Partners?
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