SYCE1 and ZNF124

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		SYCE1	ZNF124
Description		synaptonemal complex central element protein 1	zinc finger protein 124
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Central Element Nucleoplasm Chromosome Cytosol Intracellular Membrane-bounded Organelle	Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Synaptonemal Complex Assembly Cell Division	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		Meiotic synapsis	Generic Transcription Pathway
Drugs
Diseases
GWAS			Alcohol dependence ( 21314694)
Interacting Genes		49 interacting genes: ALOX5 ARNT2 BEX2 BFSP2 CBY2 CCDC102B CCHCR1 CFAP100 CINP CNN1 CYTH3 EDRF1 EXOC8 FAM161A FAM161B HAUS1 HMG20B HOOK1 HSPB1 HSPB7 IQUB KAT5 KIFC3 KRT18 LMNA MBD3 MPV17 MRFAP1L1 NME7 PSTPIP1 RALBP1 RBCK1 RUNX1T1 SCNM1 SKA1 SMARCE1 SPATC1L SSX2 STX19 TFIP11 TPM1 TPM3 TRAF1 TRIM41 TSG101 TXN2 VPS25 WASHC3 ZNF124	53 interacting genes: AMMECR1 AXIN2 BACH2 BLZF1 CCDC136 CCNDBP1 CYSRT1 DISC1 FHL5 FRS3 FSD2 GLRX3 GOLGA2 GOLGA6L9 HAP1 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-2 KRTAP5-9 LDOC1 LZTS2 MDFI MEOX2 MID2 MTUS2 NBPF19 NOTCH2NLA OGT PAX6 PDE4DIP SRRM4 SSX2IP SYCE1 TCF4 TRAF1 TRIM55 TRIM63 TSGA10 UBL5 ZMAT1 ZNF526 ZNF660 ZNF837 ZRANB1
Entrez ID		93426	7678
HPRD ID		12598	01936
Ensembl ID		ENSG00000171772	ENSG00000196418
Uniprot IDs		A0A0B4J1R9 Q8N0S2	J3QKQ6 Q15973
PDB IDs
Enriched GO Terms of Interacting Partners?
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