GTF3C4 and GTF3C5

Number of citations of the paper that reports this interaction (PubMedID 22939629)
326

Data Source:
BioGRID (biochemical)
HPRD (in vivo, in vitro)

		GTF3C4	GTF3C5
Description		general transcription factor IIIC subunit 4	general transcription factor IIIC subunit 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleoplasm Mitochondrion	Transcription Factor TFIIIC Complex Nucleoplasm
	Molecular Function	DNA Binding Histone Acetyltransferase Activity Protein Binding Enzyme Activator Activity	DNA Binding Protein Binding
	Biological Process	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter Histone Acetylation 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III Regulation Of Catalytic Activity	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter Skeletal Muscle Cell Differentiation 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III
Pathways		RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS			Sepsis (28-day mortality) ( 32592749)
Interacting Genes		14 interacting genes: AURKA BRCA1 BRF1 GTF3C1 GTF3C2 GTF3C5 GTF3C6 H3-4 H3C15 POLR3C POLR3F PRRC2B SUMO2 TBP	16 interacting genes: BRF1 DNMT3L GTF3C3 GTF3C4 GTF3C6 KRT40 KRTAP10-3 KRTAP12-3 MDFI NOTCH2NLA OGT PTEN SRA1 TBP TCF21 TCF4
Entrez ID		9329	9328
HPRD ID		11998	16077
Ensembl ID		ENSG00000125484	ENSG00000148308
Uniprot IDs		B3KNH2 Q9UKN8	H7BY84 Q9Y5Q8
PDB IDs
Enriched GO Terms of Interacting Partners?
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