GTF3C5 and GTF3C4

Number of citations of the paper that reports this interaction (PubMedID 22939629)
326

Data Source:
BioGRID (biochemical)
HPRD (in vivo, in vitro)

		GTF3C5	GTF3C4
Description		general transcription factor IIIC subunit 5	general transcription factor IIIC subunit 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleoplasm	Transcription Factor TFIIIC Complex Nucleoplasm Mitochondrion
	Molecular Function	DNA Binding Protein Binding	DNA Binding Histone Acetyltransferase Activity Protein Binding Enzyme Activator Activity
	Biological Process	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter Skeletal Muscle Cell Differentiation 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter Histone Acetylation 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III Regulation Of Catalytic Activity
Pathways		RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS		Sepsis (28-day mortality) ( 32592749)
Interacting Genes		16 interacting genes: BRF1 DNMT3L GTF3C3 GTF3C4 GTF3C6 KRT40 KRTAP10-3 KRTAP12-3 MDFI NOTCH2NLA OGT PTEN SRA1 TBP TCF21 TCF4	14 interacting genes: AURKA BRCA1 BRF1 GTF3C1 GTF3C2 GTF3C5 GTF3C6 H3-4 H3C15 POLR3C POLR3F PRRC2B SUMO2 TBP
Entrez ID		9328	9329
HPRD ID		16077	11998
Ensembl ID		ENSG00000148308	ENSG00000125484
Uniprot IDs		H7BY84 Q9Y5Q8	B3KNH2 Q9UKN8
PDB IDs
Enriched GO Terms of Interacting Partners?
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