PRDM6 and BANF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PRDM6	BANF2
Description		PR/SET domain 6	BANF family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Histone Methyltransferase Activity Identical Protein Binding Metal Ion Binding	DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Histone Methylation Neurogenesis Negative Regulation Of Smooth Muscle Cell Differentiation	Chromosome Segregation Chromosome Condensation
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28892062) Coronary artery disease ( 29212778) Diastolic blood pressure ( 27841878 27618447) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Male-pattern baldness ( 28196072) Mammographic density (dense area) ( 25342443) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Percent mammographic density ( 25342443) Pulse pressure ( 27841878 27618447) QRS duration ( 25035420) Systolic blood pressure ( 26390057 27841878 27618447 30578418)	Apolipoprotein B levels ( 32203549) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heel bone mineral density ( 30598549) LDL cholesterol levels ( 32203549 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Low density lipoprotein cholesterol levels ( 33339817)
Interacting Genes		70 interacting genes: ABI2 AGXT AHCYL1 ANKS1A AQP1 ARID5A ATPAF2 ATXN7L2 BAG3 BANF2 BANP C1orf109 CBFA2T2 CBX8 CCDC120 CCDC57 CCHCR1 CCNL1 CEP57L1 COX5B CSTF2 ELOA ENKD1 EXOSC5 FAM214B FAM90A1 FHL2 FOXD4L1 FRS3 FTO GADD45GIP1 GEM GPANK1 GRXCR1 HOXC8 IL16 IQUB KANK2 KAT5 KCTD9 KIFC3 LMO1 LMO2 LONRF1 MYOZ3 NCK2 NEK6 NFKBID PATZ1 PIH1D2 PRKAA2 PTK6 QARS1 RAD51D ROPN1 RUNX1T1 SAMD4A STK16 TCAF1 TEKT4 TLE5 TRIM14 TRMT12 TSGA10 TSGA10IP TSSK3 TTC23 UBASH3A USP54 ZFYVE26	18 interacting genes: ADAMTSL4 BANF1 BEND7 CFP CRX CRYBA1 DDIT4L DNAAF4 DUSP23 INCA1 KRTAP13-1 MACROD2 MTUS2 NTAQ1 PRDM6 PSMA1 SERTAD1 TCF4
Entrez ID		93166	140836
HPRD ID		19698	12759
Ensembl ID		ENSG00000061455	ENSG00000125888
Uniprot IDs		Q9NQX0	A0A140VK85 Q9H503
PDB IDs
Enriched GO Terms of Interacting Partners?
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