BANF2 and MACROD2

		BANF2	MACROD2
Description		BANF family member 2	mono-ADP ribosylhydrolase 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Nucleolus
	Molecular Function	DNA Binding	Hydrolase Activity, Acting On Glycosyl Bonds Deacetylase Activity ADP-ribosylglutamate Hydrolase Activity
	Biological Process	Chromosome Segregation Chromosome Condensation	Cellular Response To DNA Damage Stimulus Purine Nucleoside Metabolic Process Protein De-ADP-ribosylation Peptidyl-glutamate ADP-deribosylation
Pathways
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heel bone mineral density ( 30598549) LDL cholesterol levels ( 32203549 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Low density lipoprotein cholesterol levels ( 33339817)	Advanced glycation end-product levels ( 26915486) Age at first sexual intercourse ( 34211149) Alanine aminotransferase levels ( 33547301) Alzheimer's disease in APOE e4- carriers ( 25778476) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Asthma (childhood onset) ( 31379025) Asthma (time to childhood onset) x early life tobacco smoke interaction ( 31379025) Autism ( 20663923) Autism spectrum disorder ( 30804558) Body mass index ( 25673413) Body size at age 10 ( 32376654) Brain connectivity ( 23471985) Chronotype ( 30696823) Common carotid intima-media thickness in HIV infection ( 29206233) Congenital heart disease (transposition of the great arteries) ( 33201861) Coronary artery aneurysm in Kawasaki disease ( 27171184) Dimensional psychopathology (Negative) ( 29496196) Dimensional psychopathology (Positive) ( 29496196) Eating disorders ( 23568457) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Estimated glomerular filtration rate ( 31152163) Femoral neck bone mineral density ( 29499414) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Hip circumference ( 28552196) Intelligence (MTAG) ( 29326435) Leftâ€“right brain asymmetry ( 33723403) Male fertility ( 22633400) Medial orbital frontal cortex volume ( 31530798) Metabolite levels ( 23823483) Neurofibrillary tangles ( 31497858) Non-alcoholic fatty liver disease histology (other) ( 20708005) Obesity-related traits ( 23251661) Percentage gas trapping ( 26030696) Presence of antiphospholipid antibodies ( 27098658 23509613) Sleep duration ( 30846698) Smoking behaviour (age at first cigarette) ( 30679032) Thyroid-associated orbitopathy in graves' disease ( 27304844) Waist circumference adjusted for body mass index ( 28552196) Weight ( 28552196) White matter lesion progression ( 26451028)
Interacting Genes		18 interacting genes: ADAMTSL4 BANF1 BEND7 CFP CRX CRYBA1 DDIT4L DNAAF4 DUSP23 INCA1 KRTAP13-1 MACROD2 MTUS2 NTAQ1 PRDM6 PSMA1 SERTAD1 TCF4	4 interacting genes: BANF2 ISM1 SEL1L2 TASP1
Entrez ID		140836	140733
HPRD ID		12759	16640
Ensembl ID		ENSG00000125888	ENSG00000172264
Uniprot IDs		A0A140VK85 Q9H503	A1Z1Q3
PDB IDs			4IQY 6Y4Y 6Y4Z 6Y73
Enriched GO Terms of Interacting Partners?
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