RIPPLY1 and GRHL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RIPPLY1	GRHL3
Description		ripply transcriptional repressor 1	grainyhead like transcription factor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Chromatin DNA Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Somite Specification Embryonic Pattern Specification Somite Rostral/caudal Axis Specification Negative Regulation Of Transcription, DNA-templated	Establishment Of Planar Polarity Neural Tube Closure Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Ectoderm Development Central Nervous System Development Epidermis Development Positive Regulation Of Gene Expression Regulation Of Actin Cytoskeleton Organization Wound Healing Positive Regulation Of GTPase Activity Positive Regulation Of Transcription By RNA Polymerase II Eyelid Development In Camera-type Eye Establishment Of Skin Barrier Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure
Pathways
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Pancreatitis ( 23143602)	Cleft palate ( 28054174 27018472) Fasting blood insulin (BMI interaction) ( 22581228) Male-pattern baldness ( 28196072) Response to interferon beta in multiple sclerosis ( 26644207)
Interacting Genes		45 interacting genes: AVPI1 BEND7 CFAP58 CTNNA3 DCAF15 DIRAS2 FHL2 GRAPL GRHL3 H3-4 HAND2 HDAC7 IRAK1BP1 KRT34 MCCD1 MDFI MED19 MEOX2 NDUFB7 PATZ1 PBX4 PFDN5 PLAGL2 PRR20A PRR20B PRR20C PRR20D PRR20E PTTG2 RBPMS REL RHOH RNF144B SAPCD1 THAP1 TLE5 TRAF1 TRAF2 TRAF3 USP6 VAC14 VGLL1 ZMYND12 ZNF620 ZNF784	8 interacting genes: EAF1 ENKD1 GRHL1 GRHL2 PRMT1 PRMT5 PRMT6 RIPPLY1
Entrez ID		92129	57822
HPRD ID			12210
Ensembl ID		ENSG00000147223	ENSG00000158055
Uniprot IDs		Q0D2K3	Q8TE85
PDB IDs
Enriched GO Terms of Interacting Partners?
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