GRHL3 and GRHL1

Number of citations of the paper that reports this interaction (PubMedID 12549979)
33

Data Source:
BioGRID (pull down)
HPRD (two hybrid, in vitro)

		GRHL3	GRHL1
Description		grainyhead like transcription factor 3	grainyhead like transcription factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Chromatin DNA Binding Sequence-specific DNA Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Chromatin DNA Binding Protein Homodimerization Activity Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Establishment Of Planar Polarity Neural Tube Closure Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Ectoderm Development Central Nervous System Development Epidermis Development Positive Regulation Of Gene Expression Regulation Of Actin Cytoskeleton Organization Wound Healing Positive Regulation Of GTPase Activity Positive Regulation Of Transcription By RNA Polymerase II Eyelid Development In Camera-type Eye Establishment Of Skin Barrier Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure	Desmosome Organization Regulation Of Transcription By RNA Polymerase II Epidermis Development Regulation Of Keratinocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Establishment Of Skin Barrier
Pathways			PPARA activates gene expression
Drugs
Diseases
GWAS		Cleft palate ( 28054174 27018472) Fasting blood insulin (BMI interaction) ( 22581228) Male-pattern baldness ( 28196072) Response to interferon beta in multiple sclerosis ( 26644207)	Blood urea nitrogen levels ( 31152163) Breast cancer ( 29059683) Dental caries (decayed, missing and filled teeth) ( 31533690) Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) Prostate cancer ( 23535732) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)
Interacting Genes		8 interacting genes: EAF1 ENKD1 GRHL1 GRHL2 PRMT1 PRMT5 PRMT6 RIPPLY1	1 interacting genes: GRHL3
Entrez ID		57822	29841
HPRD ID		12210	18176
Ensembl ID		ENSG00000158055	ENSG00000134317
Uniprot IDs		Q8TE85	Q9NZI5
PDB IDs			5MPF 5MPH 5MPI
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?