HACD1 and IL10RA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HACD1	IL10RA
Description		3-hydroxyacyl-CoA dehydratase 1	interleukin 10 receptor subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane	Cytosol Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding 3-hydroxyacyl-CoA Dehydratase Activity 3R-hydroxyacyl-CoA Dehydratase Activity Very-long-chain 3-hydroxyacyl-CoA Dehydratase Activity 3-hydroxy-arachidoyl-CoA Dehydratase Activity 3-hydroxy-behenoyl-CoA Dehydratase Activity 3-hydroxy-lignoceroyl-CoA Dehydratase Activity	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Interleukin-10 Binding Signaling Receptor Activity
	Biological Process	Sphingolipid Biosynthetic Process Fatty Acid Elongation Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process	Negative Regulation Of Autophagy Cytokine-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Synapse Organization Ubiquitin-dependent Endocytosis
Pathways		Synthesis of very long-chain fatty acyl-CoAs	Interleukin-10 signaling
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Interacting Genes		8 interacting genes: CPLX4 GATA3 IL10RA LMNA RNF170 TECR TMEM106C UBC	22 interacting genes: BTRC C1QL4 CDS2 CMTM3 DRD2 HACD1 IL10 IL10RB JAK1 KMT2A MAL NIPAL4 PLPP6 RUSF1 SELENOK SLC38A7 SLC66A2 SLC7A14 SMCO4 TMEM242 TMUB2 YIPF6
Entrez ID		9200	3587
HPRD ID		10175	00911
Ensembl ID		ENSG00000165996	ENSG00000110324
Uniprot IDs		B0YJ81	Q13651
PDB IDs			1J7V 1LQS 1Y6K 1Y6M 1Y6N 5IXI
Enriched GO Terms of Interacting Partners?
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