HACD1 and CPLX4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HACD1	CPLX4
Description		3-hydroxyacyl-CoA dehydratase 1	complexin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane	Plasma Membrane SNARE Complex Terminal Bouton
	Molecular Function	Protein Binding 3-hydroxyacyl-CoA Dehydratase Activity 3R-hydroxyacyl-CoA Dehydratase Activity Very-long-chain 3-hydroxyacyl-CoA Dehydratase Activity 3-hydroxy-arachidoyl-CoA Dehydratase Activity 3-hydroxy-behenoyl-CoA Dehydratase Activity 3-hydroxy-lignoceroyl-CoA Dehydratase Activity	SNARE Binding Protein Binding Syntaxin Binding
	Biological Process	Sphingolipid Biosynthetic Process Fatty Acid Elongation Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process	Visual Perception Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Secretion Response To Stimulus
Pathways		Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS			Cardiac troponin-I levels ( 31014085) Chronotype ( 27494321) Macular thickness ( 30535121) Morning vs. evening chronotype ( 27494321)
Interacting Genes		8 interacting genes: CPLX4 GATA3 IL10RA LMNA RNF170 TECR TMEM106C UBC	92 interacting genes: ADIPOQ AGTRAP AIG1 AOC3 APOD AQP1 AQP9 ASGR1 ATP6V0C BNIP2 C14orf180 C1GALT1 C3orf52 C5 CACNG1 CCL4L2 CD81 CDIPT CDS2 CLDND2 CLEC4G CLN6 CMTM5 CNIH1 CTSA CTXN3 CYB5B CYBC1 CYP4F2 DEFB127 EMD GAD2 GIMAP1 GRM2 HACD1 HHATL HMOX1 INSIG2 LPAR3 MAL MALL MAN2B2 MGAM NINJ2 NRM ORMDL1 PGAP2 PLN PLP2 PLPP4 PNLIPRP1 PTPN9 RTP2 SEC22B SELENOK SFTPC SLC30A2 SLC30A8 SLC35A1 SLC35A4 SLC35B4 SLC38A7 SLC39A9 SMCO4 STX3 STX8 SYNJ2BP TF TMEM120B TMEM14A TMEM14B TMEM19 TMEM201 TMEM203 TMEM218 TMEM229B TMEM243 TMEM254 TMEM267 TMEM60 TMEM79 TMEM86A TMEM97 TRAF3IP3 TSPO2 UBIAD1 VAMP4 VAMP5 VKORC1 WFDC2 YIPF6 ZFPL1
Entrez ID		9200	339302
HPRD ID		10175	13091
Ensembl ID		ENSG00000165996	ENSG00000166569
Uniprot IDs		B0YJ81	Q7Z7G2
PDB IDs
Enriched GO Terms of Interacting Partners?
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