YTHDC1 and SRSF1

Number of citations of the paper that reports this interaction (PubMedID 9473574)
18

Data Source:
HPRD (in vitro, two hybrid)

		YTHDC1	SRSF1
Description		YTH domain containing 1	serine and arginine rich splicing factor 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Plasma Membrane Nuclear Speck	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding N6-methyladenosine-containing RNA Binding	RNA Binding MRNA Binding Protein Binding Protein Kinase B Binding DNA Topoisomerase Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Splice Site Selection MRNA Export From Nucleus Spermatogenesis Dosage Compensation By Inactivation Of X Chromosome Posttranscriptional Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Primary Follicle Stage MRNA Alternative Polyadenylation	Alternative MRNA Splicing, Via Spliceosome MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing Positive Regulation Of RNA Splicing Oligodendrocyte Differentiation MRNA Transport Liver Regeneration
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs			Copper
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Obesity-related traits ( 23251661)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		42 interacting genes: ABL1 ADAMTS4 ANKRD28 CFH CLK1 CLK2 CORO1A DVL3 EDC4 EMD FYN GOLGA2 HNRNPK KHDRBS1 KHDRBS2 KHDRBS3 KRT18 KRTAP10-6 LAMC3 LAMTOR5 LZTS2 MPRIP PHF19 PICK1 PLG PROSER2 RBMY1A1 RBMY1F RBMY1J RNPS1 SDCBP2 SEPTIN10 SOX13 SRC SRPK1 SRPK2 SRSF1 SRSF2 TRA2A TRA2B TXK VPS51	42 interacting genes: AKAP17A APP BCL10 C1QBP CACNA1A CD8A CDC42 CDK12 CDK6 CLK1 DANCR DIDO1 DYRK1A GEMIN2 HIPK3 HNRNPA0 LNX1 LUC7L3 NFYA NXF1 PPARG PRPF4 PRPF4B PSIP1 RNPS1 SCAF11 SNRNP70 SREK1 SRPK1 SRPK2 SRSF10 SRSF11 SRSF5 TCERG1 TNPO3 TOP1 TP53 U2AF1 U2AF2 XBP1 YTHDC1 ZRSR2
Entrez ID		91746	6426
HPRD ID		11689	02887
Ensembl ID		ENSG00000083896	ENSG00000136450
Uniprot IDs		J3QR07 Q96MU7	Q07955 Q59FA2
PDB IDs		2YUD 4R3H 4R3I 6RT4 6RT5 6RT6 6RT7 6SYZ 6SZ1 6SZ2 6SZ3 6SZL 6SZN 6SZR 6SZT 6SZX 6SZY 6T01 6T02 6T03 6T04 6T05 6T06 6T07 6T08 6T09 6T0A 6T0C 6T0D 6T0O 6T0X 6T0Z 6T10 6T11 6T12 6WE8 6WE9 6WEA 6YKE 6YKI 6YKJ 6YKZ 6YL0 6YL8 6YL9 6YNI 6YNJ 6YNK 6YNL 6YNM 6YNN 6YNO 6YNP 6YOQ 6ZCM 6ZCN 6ZD9	1X4A 2M7S 2M8D 2O3D 3BEG 4C0O 6HPJ 7ABG
Enriched GO Terms of Interacting Partners?
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