CBFA2T2 and TAL2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		CBFA2T2	TAL2
Description		CBFA2/RUNX1 partner transcriptional co-repressor 2	TAL bHLH transcription factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin
	Molecular Function	Transcription Corepressor Activity Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription, DNA-templated Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Negative Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Intestinal Epithelial Cell Differentiation	Regulation Of Transcription By RNA Polymerase II Post-embryonic Development Thalamus Development Midbrain Development Multicellular Organism Growth
Pathways
Drugs
Diseases
GWAS		Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Triglyceride levels ( 32203549)	Cognitive performance ( 20125193) Cutaneous malignant melanoma ( 26237428) Melanoma ( 28212542) Menarche (age at onset) ( 19448620) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		34 interacting genes: APP ATN1 ATXN1L BAG4 CBFA2T3 CBFB CEP83 FBXL19 GTF2E1 ID3 KIFC3 KRTAP13-2 LBP MAGEA6 MDFI NCOR1 NCOR2 NEUROG1 NOTCH3 NTAQ1 PDP1 PHAF1 PRDM14 PRDM6 RERE RUNX1 SIKE1 SIN3A SORBS3 TAL2 TCF4 TCP1 ZC2HC1A ZNF652	11 interacting genes: CBFA2T2 CDK6 HLA-DQA1 LMO1 LMO2 MAPK3 PCBD2 RUNX1T1 TCF12 TCF3 TCF4
Entrez ID		9139	6887
HPRD ID		04721	01735
Ensembl ID		ENSG00000078699	ENSG00000186051
Uniprot IDs		O43439	Q16559
PDB IDs
Enriched GO Terms of Interacting Partners?
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