SMC3 and RPGR

Number of citations of the paper that reports this interaction (PubMedID 16043481)
69

Data Source:
BioGRID (pull down)
HPRD (in vitro, in vivo)

		SMC3	RPGR
Description		structural maintenance of chromosomes 3	retinitis pigmentosa GTPase regulator
Image
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Lateral Element Nucleoplasm Chromosome Cytosol Cohesin Complex Nuclear Matrix Meiotic Cohesin Complex Nuclear Mitotic Cohesin Complex Nuclear Meiotic Cohesin Complex Mitotic Spindle Pole	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum
	Molecular Function	Chromatin Binding Double-stranded DNA Binding Microtubule Motor Activity Protein Binding ATP Binding Mediator Complex Binding Protein Heterodimerization Activity Beta-tubulin Binding Cohesin Loading Activity Dynein Complex Binding	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Mitotic Cell Cycle Regulation Of DNA Replication DNA Repair Sister Chromatid Cohesion Mitotic Sister Chromatid Cohesion Stem Cell Population Maintenance Cell Division Meiotic Cell Cycle Mitotic Spindle Assembly	Intracellular Protein Transport Visual Perception Intraciliary Transport Regulation Of Catalytic Activity Response To Stimulus Cilium Assembly
Pathways		Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Acute respiratory distress syndrome in sepsis ( 31982041) Lumbar spine bone mineral density (integral) ( 27476799) Metabolite levels ( 23823483)
Interacting Genes		19 interacting genes: APC CEP63 CYP27B1 DISC1 ESCO2 ESR1 FEZ1 FEZ2 KIFAP3 MTNR1B MXD1 MXD3 MXD4 MXI1 RPGR SMC1A SMC1B SUMO2 TRAF3IP1	19 interacting genes: ATP6AP2 DCTN1 DCTN2 HOMEZ IFT88 KIF3A KIFAP3 NPM1 NUDT12 PDE6D RPGRIP1 SLC25A10 SLC9A7 SMC1A SMC3 TSPAN7 TUBG1 USP9X YWHAE
Entrez ID		9126	6103
HPRD ID		05829	02425
Ensembl ID		ENSG00000108055	ENSG00000156313
Uniprot IDs		Q9UQE7	Q92834
PDB IDs		6WG3 6WG4 6WG6 6WGE	4JHN 4JHP 4QAM
Enriched GO Terms of Interacting Partners?
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