PDLIM1 and STK35

Number of citations of the paper that reports this interaction (PubMedID 11973348)
23

Data Source:
HPRD (in vitro, two hybrid)

		PDLIM1	STK35
Description		PDZ and LIM domain 1	serine/threonine kinase 35
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Transcription Regulator Complex Cytoplasm Cytoskeleton Adherens Junction Focal Adhesion Z Disc Filamentous Actin	Nucleus Nucleoplasm Nucleolus Cytoplasm Nuclear Body
	Molecular Function	Transcription Coactivator Activity Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding Cadherin Binding Involved In Cell-cell Adhesion	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Response To Hypoxia Regulation Of Transcription By RNA Polymerase II Response To Oxidative Stress Heart Development Fibroblast Migration Maintenance Of Cell Polarity Actin Cytoskeleton Organization Establishment Or Maintenance Of Actin Cytoskeleton Polarity Stress Fiber Assembly Positive Regulation Of Transcription, DNA-templated Muscle Structure Development Cell-cell Adhesion	Protein Phosphorylation Meiotic Cell Cycle
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Hemoglobin ( 32888494) Mean platelet volume ( 32888494 27863252) Suicide risk ( 21041247) White blood cell count ( 32888494)	Adult body size ( 32376654) Basal cell carcinoma ( 33549134) Early spontaneous preterm birth ( 31194736) Immune response to measles-mumps-rubella vaccine ( 24811271) Keratoconus ( 33649486) Plateletcrit ( 32888494) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		14 interacting genes: ACTN1 ACTN2 ACTN4 AGK GFAP MAPK6 PGS1 PITX2 PTGER4 RLIM RPS6KA5 STK35 SUPT4H1 VIM	6 interacting genes: BMPR1B OSBPL3 PDLIM1 SMAD4 SMURF1 TGFBR1
Entrez ID		9124	140901
HPRD ID		09326	11612
Ensembl ID		ENSG00000107438	ENSG00000125834
Uniprot IDs		O00151 V9HW92	Q8TDR2
PDB IDs		1X62 2PKT
Enriched GO Terms of Interacting Partners?
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