IGFN1 and DDAH2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		IGFN1	DDAH2
Description		immunoglobulin like and fibronectin type III domain containing 1	dimethylarginine dimethylaminohydrolase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Z Disc Synapse	Mitochondrion Cytosol Extracellular Exosome
	Molecular Function	Protein Binding	Catalytic Activity Protein Binding Dimethylargininase Activity Amino Acid Binding
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Synapse Assembly Biological_process Retina Layer Formation	Citrulline Metabolic Process Arginine Metabolic Process Arginine Catabolic Process Nitric Oxide Biosynthetic Process Nitric Oxide Mediated Signal Transduction Negative Regulation Of Apoptotic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric-oxide Synthase Activity
Pathways			eNOS activation
Drugs			Citrulline
Diseases
GWAS		Asthma ( 29273806) Height ( 28552196)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Ulcerative colitis ( 28067908)
Interacting Genes		40 interacting genes: BANP BLZF1 C19orf54 COG6 CRX DDAH2 FXR2 GOLGA2 HIVEP1 HOXA1 HOXD3 KCTD9 KIFC3 KRT39 KRTAP6-2 LHX9 LZTS2 MEOX2 MID2 MYOD1 NHLRC4 PIBF1 PNMA1 POF1B POU6F2 PRKAR1B PRR23B SERTAD2 SPAG5 TAX1BP1 TRIM21 TRIM27 TRIM35 TRIM42 TRIP13 TSC1 UBAP2 USP54 ZNF620 ZNF688	28 interacting genes: ACTN3 ANXA7 ATP1B1 CDC73 CDK4 CDKN1A DNAJB11 FANCL GADD45G IGFN1 MAP3K20 MKNK1 NOXA1 PIN1 PRKAB2 RAP1B RCC1 RPS6KA1 RPS6KA5 SCGN SMN1 STK3 TAF1D TK1 TNFSF11 TRIP13 TSC22D1 VAC14
Entrez ID		91156	23564
HPRD ID		16812	09204
Ensembl ID		ENSG00000163395	ENSG00000213722
Uniprot IDs		Q86VF2	O95865 V9HW53
PDB IDs
Enriched GO Terms of Interacting Partners?
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