DDAH2 and IGFN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DDAH2	IGFN1
Description		dimethylarginine dimethylaminohydrolase 2	immunoglobulin like and fibronectin type III domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Extracellular Exosome	Nucleus Z Disc Synapse
	Molecular Function	Catalytic Activity Protein Binding Dimethylargininase Activity Amino Acid Binding	Protein Binding
	Biological Process	Citrulline Metabolic Process Arginine Metabolic Process Arginine Catabolic Process Nitric Oxide Biosynthetic Process Nitric Oxide Mediated Signal Transduction Negative Regulation Of Apoptotic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric-oxide Synthase Activity	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Synapse Assembly Biological_process Retina Layer Formation
Pathways		eNOS activation
Drugs		Citrulline
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Ulcerative colitis ( 28067908)	Asthma ( 29273806) Height ( 28552196)
Interacting Genes		28 interacting genes: ACTN3 ANXA7 ATP1B1 CDC73 CDK4 CDKN1A DNAJB11 FANCL GADD45G IGFN1 MAP3K20 MKNK1 NOXA1 PIN1 PRKAB2 RAP1B RCC1 RPS6KA1 RPS6KA5 SCGN SMN1 STK3 TAF1D TK1 TNFSF11 TRIP13 TSC22D1 VAC14	40 interacting genes: BANP BLZF1 C19orf54 COG6 CRX DDAH2 FXR2 GOLGA2 HIVEP1 HOXA1 HOXD3 KCTD9 KIFC3 KRT39 KRTAP6-2 LHX9 LZTS2 MEOX2 MID2 MYOD1 NHLRC4 PIBF1 PNMA1 POF1B POU6F2 PRKAR1B PRR23B SERTAD2 SPAG5 TAX1BP1 TRIM21 TRIM27 TRIM35 TRIM42 TRIP13 TSC1 UBAP2 USP54 ZNF620 ZNF688
Entrez ID		23564	91156
HPRD ID		09204	16812
Ensembl ID		ENSG00000213722	ENSG00000163395
Uniprot IDs		O95865 V9HW53	Q86VF2
PDB IDs
Enriched GO Terms of Interacting Partners?
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