ZFAND2A and RNF216

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZFAND2A	RNF216
Description		zinc finger AN1-type containing 2A	ring finger protein 216
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Nucleus Cytoplasm Endoplasmic Reticulum	Nucleus Nucleoplasm Cytosol Schaffer Collateral - CA1 Synapse Postsynaptic Endocytic Zone Glutamatergic Synapse
	Molecular Function	Protein Binding Zinc Ion Binding	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Targeting To ER Cellular Response To Arsenic-containing Substance	Apoptotic Process Negative Regulation Of Type I Interferon Production Regulation Of Interferon-beta Production Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Defense Response To Virus By Host Protein K48-linked Ubiquitination Protein Catabolic Process, Modulating Synaptic Transmission
Pathways			Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) GLP-1 levels in response to oral glucose tolerance test (fasting) ( 29093273) High light scatter reticulocyte percentage of red cells ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401)	Parkinson's disease motor subtype (tremor to postural instability/gait difficulty score ratio) ( 33987465)
Interacting Genes		7 interacting genes: DAZAP2 LIG4 PLEKHB2 RNF216 RPL30 TRIM23 UBQLN2	30 interacting genes: AGFG1 BRCA1 CAPN15 FAM168A KIR2DL4 MAPK1 MORC3 OPTN RIPK1 RNF11 SUMO2 TLR3 TLR4 TLR5 TLR9 TNFAIP3 TRAF3 UBAC1 UBASH3A UBASH3B UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2L3 UBE2L6 USP5 YOD1 ZFAND2A
Entrez ID		90637	54476
HPRD ID		14277	15550
Ensembl ID		ENSG00000178381	ENSG00000011275
Uniprot IDs		Q8N6M9	A8K8N1 Q9NWF9
PDB IDs
Enriched GO Terms of Interacting Partners?
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