ZNF439 and GMNN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		ZNF439	GMNN
Description		zinc finger protein 439	geminin DNA replication inhibitor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Chromatin Binding Transcription Corepressor Activity Protein Binding Histone Deacetylase Binding DNA-binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA Replication Negative Regulation Of DNA Replication Animal Organ Morphogenesis Positive Regulation Of Chromatin Binding Negative Regulation Of Cell Cycle Negative Regulation Of Transcription, DNA-templated DNA Replication Preinitiation Complex Assembly Negative Regulation Of DNA-dependent DNA Replication
Pathways		Generic Transcription Pathway	CDT1 association with the CDC6:ORC:origin complex Activation of the pre-replicative complex
Drugs
Diseases
GWAS		Academic attainment (English) ( 33594131)	Metabolite levels ( 23823483)
Interacting Genes		24 interacting genes: CARD10 CCNDBP1 CEP70 CYSRT1 GMNN KRT40 KRTAP1-1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-12 KRTAP5-9 KRTAP9-3 LMNA MDFI MTUS2 NOTCH2NLA PLEKHF2 TIMM29 TRIM41	34 interacting genes: ARNT AURKA CASP3 CCDC146 CDC20 CDKN1A CDKN2A CDT1 CSNK2A1 FZR1 GLIS2 HOXA10 HOXA11 HOXA7 HOXB7 HOXC8 HOXC9 HOXD10 IMPDH1 KANK2 KAT7 LNX1 MCM6 NCF1 PHC1 PTPN11 REPIN1 SAPCD2 SCMH1 SHANK2 SIX3 SMARCA4 ZNF250 ZNF439
Entrez ID		90594	51053
HPRD ID		11717	06783
Ensembl ID		ENSG00000171291	ENSG00000112312
Uniprot IDs		A0A0C4DG37 Q8NDP4	A0A024QZY7 O75496
PDB IDs			1T6F 1UII 2LP0 2WVR 4BRY
Enriched GO Terms of Interacting Partners?
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