SH2D2A and ZYG11B

		SH2D2A	ZYG11B
Description		SH2 domain containing 2A	zyg-11 family member B, cell cycle regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Cul2-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding SH3 Domain Binding	Protein Binding
	Biological Process	Angiogenesis Signal Transduction Cell Population Proliferation Cell Differentiation	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways		VEGFA-VEGFR2 Pathway
Drugs
Diseases
GWAS		Autoimmune thyroid disease ( 32581359) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) SjÃ¶gren's syndrome ( 28076899)	Monocyte percentage of white cells ( 32888494)
Interacting Genes		35 interacting genes: APPL1 AR ARID5A CRK DAPK1 EGFR ERBB2 ERBB3 ERBB4 GAB1 ITK KDR KIT LCK LINC02875 LNX1 LRRFIP1 LRRK1 MAP3K2 MAPK7 MET MFHAS1 NAA16 PLCG1 PPP1R21 SOCS3 SPTB STAT3 SYK TSC1 TXK VCP ZHX3 ZSCAN1 ZYG11B	14 interacting genes: ARPC2 ASPA BTBD2 BTF3L4 CFL2 CUL2 ELOB ELOC GBF1 NDC1 OSBPL9 SH2D2A TLR6 UCK2
Entrez ID		9047	79699
HPRD ID		05152	13356
Ensembl ID		ENSG00000027869	ENSG00000162378
Uniprot IDs		Q5UBZ2 Q5UBZ3 Q9NP31	A8DPD7 B4DK95 Q9C0D3
PDB IDs
Enriched GO Terms of Interacting Partners?
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