HiPPIP
  • Home
  • About
  • SZ Genes
  • People
  • Help
  • Advanced Search

ZYG11B and ASPA

ZYG11B

ASPA

Description zyg-11 family member B, cell cycle regulator aspartoacylase
Image No pdb structure
GO Annotations Cellular Component
  • Cul2-RING Ubiquitin Ligase Complex
  • Nucleus
  • Cytosol
Molecular Function
  • Protein Binding
  • Aminoacylase Activity
  • Protein Binding
  • Hydrolase Activity, Acting On Ester Bonds
  • Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides
  • Aspartoacylase Activity
  • Identical Protein Binding
  • Metal Ion Binding
Biological Process
  • Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins
  • Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
  • Aspartate Catabolic Process
  • Central Nervous System Myelination
  • Positive Regulation Of Oligodendrocyte Differentiation
Pathways
  • Aspartate and asparagine metabolism
Drugs
  • Aspartic acid
  • Zinc
  • Zinc acetate
  • Zinc chloride
  • Zinc sulfate, unspecified form
Diseases
GWAS
  • Monocyte percentage of white cells ( 32888494)
  • Myopia (pathological) ( 23049088)
Interacting Genes 14 interacting genes: ARPC2 ASPA BTBD2 BTF3L4 CFL2 CUL2 ELOB ELOC GBF1 NDC1 OSBPL9 SH2D2A TLR6 UCK2 3 interacting genes: ACY3 DUSP29 ZYG11B
Entrez ID 79699 443
HPRD ID 13356 02033
Ensembl ID ENSG00000162378 ENSG00000108381
Uniprot IDs A8DPD7 B4DK95 Q9C0D3 P45381 Q6FH48
PDB IDs 2I3C 2O4H 2O53 2Q51 4MRI 4MXU 4NFR 4TNU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?

© Madhavi K. Ganapathiraju 2012-2025