NAT8 and JPH1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NAT8	JPH1
Description		N-acetyltransferase 8 (putative)	junctophilin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Nucleoplasm Endoplasmic Reticulum Membrane Plasma Membrane Junctional Sarcoplasmic Reticulum Membrane Integral Component Of Membrane Sarcoplasmic Reticulum Z Disc Junctional Membrane Complex
	Molecular Function	Lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Protein Binding N-acetyltransferase Activity Cysteine-S-conjugate N-acetyltransferase Activity	Molecular_function Protein Binding Structural Constituent Of Muscle
	Biological Process	Glutathione Metabolic Process Response To Xenobiotic Stimulus Positive Regulation Of Gene Expression Peptidyl-lysine N6-acetylation Negative Regulation Of Apoptotic Process Amyloid-beta Metabolic Process Amyloid Fibril Formation	Muscle Organ Development Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcium Ion Transport Into Cytosol
Pathways		Amyloid fiber formation
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Chronic kidney disease ( 20383146) Creatinine levels ( 20383145) Estimated glomerular filtration rate ( 31015462 30604766) Glomerular filtration rate ( 23535967) Glomerular filtration rate (creatinine) ( 28452372) Hemoglobin levels ( 32327693) Macrovascular complications in type 2 diabetes ( 33430853) Metabolic traits ( 21886157) Metabolite levels ( 21931564) Metabolite levels (X-11787) ( 23934736) Serum metabolite concentrations in chronic kidney disease ( 33838163 29545352) Serum metabolite levels ( 33031748 24625756 23093944) Urinary metabolite levels in chronic kidney disease ( 29545352 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) Urinary metabolite ratios in chronic kidney disease ( 29545352) Urinary metabolites ( 26352407)	Carotid plaque burden (smoking interaction) ( 24954085) Uterine fibroids ( 28836065)
Interacting Genes		36 interacting genes: ARL13B ATP6V0E1 BIK CD3E CD59 CD79A CERS4 CREB3L1 EBP FAM209A FFAR2 GOLT1A GPR152 HSD17B13 JPH1 LEPROTL1 LMNA MFSD14B MTIF3 NAT8B REEP2 SAR1A SLC10A6 SLC40A1 SMAD4 SMYD5 SSB ST6GAL1 TGFBR1 TLCD4 TMEM143 TMEM14B TMEM31 TMX2 TSPAN31 YIPF4	15 interacting genes: AQP6 EDDM3B EMP1 GPR42 HTATIP2 LEPROTL1 MEOX2 NAT8 PLP1 SLC16A13 STRIT1 TMEM120B TMEM65 TTN UACA
Entrez ID		9027	56704
HPRD ID		08413	07286
Ensembl ID		ENSG00000144035	ENSG00000104369
Uniprot IDs		Q9UHE5	Q7Z682 Q86VR1 Q9HDC5
PDB IDs
Enriched GO Terms of Interacting Partners?
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