NAT8 and TLCD4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NAT8	TLCD4
Description		N-acetyltransferase 8 (putative)	TLC domain containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Cellular_component Endoplasmic Reticulum Integral Component Of Membrane
	Molecular Function	Lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Protein Binding N-acetyltransferase Activity Cysteine-S-conjugate N-acetyltransferase Activity	Molecular_function Protein Binding
	Biological Process	Glutathione Metabolic Process Response To Xenobiotic Stimulus Positive Regulation Of Gene Expression Peptidyl-lysine N6-acetylation Negative Regulation Of Apoptotic Process Amyloid-beta Metabolic Process Amyloid Fibril Formation	Biological_process Lipid Homeostasis
Pathways		Amyloid fiber formation
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Chronic kidney disease ( 20383146) Creatinine levels ( 20383145) Estimated glomerular filtration rate ( 31015462 30604766) Glomerular filtration rate ( 23535967) Glomerular filtration rate (creatinine) ( 28452372) Hemoglobin levels ( 32327693) Macrovascular complications in type 2 diabetes ( 33430853) Metabolic traits ( 21886157) Metabolite levels ( 21931564) Metabolite levels (X-11787) ( 23934736) Serum metabolite concentrations in chronic kidney disease ( 33838163 29545352) Serum metabolite levels ( 33031748 24625756 23093944) Urinary metabolite levels in chronic kidney disease ( 29545352 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) Urinary metabolite ratios in chronic kidney disease ( 29545352) Urinary metabolites ( 26352407)
Interacting Genes		36 interacting genes: ARL13B ATP6V0E1 BIK CD3E CD59 CD79A CERS4 CREB3L1 EBP FAM209A FFAR2 GOLT1A GPR152 HSD17B13 JPH1 LEPROTL1 LMNA MFSD14B MTIF3 NAT8B REEP2 SAR1A SLC10A6 SLC40A1 SMAD4 SMYD5 SSB ST6GAL1 TGFBR1 TLCD4 TMEM143 TMEM14B TMEM31 TMX2 TSPAN31 YIPF4	72 interacting genes: ADGRB3 ADGRE2 ARV1 ATP13A1 BNIP3 CACNG1 CCDC167 CDIPT CHPT1 CLCN7 CLEC7A CMTM5 COMT CTXN3 CXCL16 CYP4F2 CYP4F22 DHRSX EBP EMC6 EMP1 ERG28 FA2H FDFT1 FXYD6 FXYD6-FXYD2 GJB2 GOSR2 GYPA HMOX1 IGFBP5 KRT1 LNPEP MIR137HG MS4A13 MYG1 NAT8 NDUFA3 NINJ1 NKG7 ORMDL1 PMP22 PRAF2 PRRT2 REEP6 SCAMP5 SCD SEC22A SEC22B SERP1 SFXN1 SFXN3 SLC22A18 SLC41A1 SMAGP STATH STX12 SYNDIG1 SYNJ2BP TIMM23 TMEM115 TMEM120B TMEM19 TMEM229B TMEM237 TMEM60 TMIE TVP23B UBE2J1 VEZT YIPF1 YIPF4
Entrez ID		9027	148534
HPRD ID		08413	08110
Ensembl ID		ENSG00000144035	ENSG00000152078
Uniprot IDs		Q9UHE5	Q96MV1
PDB IDs
Enriched GO Terms of Interacting Partners?
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