UCN2 and IL10RB

Number of citations of the paper that reports this interaction (PubMedID 11416224)
231

Data Source:
HPRD (in vitro)

		UCN2	IL10RB
Description		urocortin 2	interleukin 10 receptor subunit beta
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Membrane Interleukin-28 Receptor Complex
	Molecular Function	Hormone Activity Hormone Binding Corticotropin-releasing Hormone Receptor Binding Corticotropin-releasing Hormone Receptor 2 Binding	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Signaling Receptor Activity
	Biological Process	Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Digestion Hormone-mediated Signaling Pathway Cellular Response To Nutrient Levels	Inflammatory Response Immune Response Signal Transduction Cytokine-mediated Signaling Pathway Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Defense Response To Virus Positive Regulation Of Cellular Respiration
Pathways		Class B/2 (Secretin family receptors)	Other interleukin signaling Interleukin-10 signaling Interleukin-20 family signaling
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908 25082827)	Blood protein levels ( 30072576) Crohn's disease ( 23128233) Multiple sclerosis ( 31604244) Narcolepsy ( 24204295 23459209)
Interacting Genes		2 interacting genes: CRHR2 IL10RB	9 interacting genes: CBR3 IFNL2 IFNL3 IL10 IL10RA IL22 RCAN1 UCN2 UCN3
Entrez ID		90226	3588
HPRD ID		16171	00473
Ensembl ID		ENSG00000145040	ENSG00000243646
Uniprot IDs		Q96RP3	Q08334
PDB IDs		2RMG 3N95	3LQM 5T5W
Enriched GO Terms of Interacting Partners?
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