TSC22D1 and GNB5

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		TSC22D1	GNB5
Description		TSC22 domain family member 1	G protein subunit beta 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytoplasm Cytosol Heterotrimeric G-protein Complex Presynapse GTPase Activator Complex
	Molecular Function	Protein Binding	GTPase Activity GTPase Activator Activity Protein Binding Signaling Receptor Complex Adaptor Activity G-protein Gamma-subunit Binding Chaperone Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II	Signal Transduction G Protein-coupled Receptor Signaling Pathway Dopamine Receptor Signaling Pathway Light Adaption Positive Regulation Of GTPase Activity Negative Regulation Of Voltage-gated Calcium Channel Activity Dark Adaptation
Pathways			Activation of G protein gated Potassium channels G-protein activation Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion ADP signalling through P2Y purinoceptor 12 G beta:gamma signalling through PI3Kgamma Prostacyclin signalling through prostacyclin receptor Prostacyclin signalling through prostacyclin receptor Adrenaline,noradrenaline inhibits insulin secretion Adrenaline,noradrenaline inhibits insulin secretion Ca2+ pathway Ca2+ pathway G alpha (q) signalling events G alpha (12/13) signalling events G beta:gamma signalling through PLC beta G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events G alpha (z) signalling events Glucagon-type ligand receptors Thromboxane signalling through TP receptor Vasopressin regulates renal water homeostasis via Aquaporins Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding G beta:gamma signalling through BTK G beta:gamma signalling through CDC42 Extra-nuclear estrogen signaling ADORA2B mediated anti-inflammatory cytokines production Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Diseases
GWAS		Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Body mass index ( 25760438) Refractive error ( 32231278) Rosacea symptom severity ( 29771307)	Lewy body disease ( 25188341)
Interacting Genes		56 interacting genes: A2M APLP1 ASAH1 CACNA1A CARHSP1 CCDC88C CCDC90B CHD3 CKAP2 CORO2B CRMP1 DDAH2 DNASE1 DNMT3B EED ERG28 FAF1 FAM20C FBN3 GNB2 GNB5 GORASP2 GTF2F2 HMGXB4 KMT2B KMT2C LPAR6 LRIF1 MAP3K12 MCM3AP NCOA5 NTAQ1 OTUB1 PDHB PRKCI PTN QARS1 RFXAP RGS1 RPL5 SETDB1 SP110 SPACA9 SPRED1 TAF5L TGFBR1 TLE1 TP53 TSC22D4 UBE2D1 UNC119 VIM WDR73 WIZ WNK1 ZC3HC1	27 interacting genes: ANXA7 APP BNIP3L CDKN1A CSNK2B DRD2 E2F2 EIF3J GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNGT1 MCM2 MVD NR6A1 OLFM2 PSD PSMD4 RGS11 RGS6 RGS7 RGS9 RPA1 TSC22D1
Entrez ID		8848	10681
HPRD ID		07414	09191
Ensembl ID		ENSG00000102804	ENSG00000069966
Uniprot IDs		A0A024RDV8 A0A087X0H8 A8K3Y6 Q15714	A0A024R5R9 A0A024R5V3 O14775
PDB IDs
Enriched GO Terms of Interacting Partners?
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