RGS9 and DRD3

Number of citations of the paper that reports this interaction (PubMedID 32828283)
0

Data Source:
BioGRID (pull down)

		RGS9	DRD3
Description		regulator of G protein signaling 9	dopamine receptor D3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Postsynaptic Density Membrane Glutamatergic Synapse	Plasma Membrane Integral Component Of Plasma Membrane Endocytic Vesicle Cell Projection Apical Part Of Cell Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Postsynaptic Density Membrane
	Molecular Function	GTPase Activity GTPase Activator Activity	Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go G Protein-coupled Receptor Activity Protein Binding Protein Domain Specific Binding D1 Dopamine Receptor Binding
	Biological Process	Response To Amphetamine G Protein-coupled Receptor Signaling Pathway Dopamine Receptor Signaling Pathway Nervous System Development Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Response To Estradiol Intracellular Signal Transduction Light Adaption Regulation Of Catalytic Activity Positive Regulation Of NMDA Glutamate Receptor Activity Regulation Of Calcium Ion Export Across Plasma Membrane Dark Adaptation	Negative Regulation Of Transcription By RNA Polymerase II Synaptic Transmission, Dopaminergic G Protein-coupled Receptor Internalization Cellular Calcium Ion Homeostasis Autophagy G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Learning Or Memory Learning Locomotory Behavior Positive Regulation Of Cell Population Proliferation Visual Learning Response To Xenobiotic Stimulus Regulation Of Dopamine Secretion Negative Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of Cytokinesis Circadian Regulation Of Gene Expression Response To Histamine Social Behavior Gastric Emptying Positive Regulation Of Renal Sodium Excretion Response To Cocaine Dopamine Metabolic Process Negative Regulation Of Apoptotic Process Regulation Of Potassium Ion Transport Response To Morphine Regulation Of Circadian Sleep/wake Cycle, Sleep Response To Ethanol Negative Regulation Of Blood Pressure Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Transcription By RNA Polymerase II Acid Secretion Behavioral Response To Cocaine Negative Regulation Of Oligodendrocyte Differentiation Arachidonic Acid Secretion Negative Regulation Of Protein Secretion Musculoskeletal Movement, Spinal Reflex Action Negative Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Synaptic Transmission, Glutamatergic Prepulse Inhibition Phospholipase C-activating Dopamine Receptor Signaling Pathway Positive Regulation Of Dopamine Receptor Signaling Pathway Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Locomotion Involved In Locomotory Behavior Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Negative Regulation Of Voltage-gated Calcium Channel Activity
Pathways		G alpha (i) signalling events G alpha (i) signalling events Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	Dopamine receptors G alpha (i) signalling events
Drugs			Ziprasidone Cabergoline Ropinirole Olanzapine Clozapine Sulpiride Loxapine Remoxipride Pramipexole Chlorpromazine Buspirone Haloperidol Amoxapine Lisuride Apomorphine Dopamine Ergoloid mesylate Pimozide Domperidone Pergolide Bromocriptine Quetiapine Levodopa Aripiprazole Chlorprothixene Paliperidone Yohimbine Methotrimeprazine Iloperidone Rotigotine ACP-104 Cariprazine Mianserin Asenapine Amisulpride Sarizotan Sumanirole Captodiame AS-8112 Blonanserin Pipamperone Tianeptine Dihydro-alpha-ergocryptine Epicriptine Pardoprunox Piribedil Tiapride Dihydroergocristine Aripiprazole lauroxil
Diseases
GWAS		Adverse response to antithyroid drugs in Graves disease ( 30067105) Heel bone mineral density ( 30598549 28869591)	Chronotype ( 30696823) Feeling hurt ( 29500382) Personality dimensions ( 23903073) Smooth-surface caries ( 24556642)
Interacting Genes		6 interacting genes: ADRB2 DRD3 GNAT1 GNB5 GUCY2D RGS9BP	20 interacting genes: CLIC6 DRD1 EEF1B2 EEF1G EPB41 EPB41L1 EPB41L2 FLNA GIPC1 GNAI1 GRB2 GSK3B MPDZ NCK1 NCS1 POLE2 RDX RGS9 SPTSSB USP48
Entrez ID		8787	1814
HPRD ID		04962	00540
Ensembl ID		ENSG00000108370	ENSG00000151577
Uniprot IDs		A8K1G1 O75916	A1A4V4 A8K8E4 E9PCM4 P35462 X5D2G4
PDB IDs			3PBL
Enriched GO Terms of Interacting Partners?
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