DRD3 and RDX

Number of citations of the paper that reports this interaction (PubMedID 14499480)
18

Data Source:
BioGRID (two hybrid)

		DRD3	RDX
Description		dopamine receptor D3	radixin
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Endocytic Vesicle Cell Projection Apical Part Of Cell Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Postsynaptic Density Membrane	Extracellular Space Plasma Membrane Microvillus Adherens Junction Focal Adhesion Apical Plasma Membrane Lamellipodium Filopodium T-tubule Midbody Cortical Actin Cytoskeleton Cleavage Furrow Cell Tip Extracellular Exosome Cell Periphery
	Molecular Function	Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go G Protein-coupled Receptor Activity Protein Binding Protein Domain Specific Binding D1 Dopamine Receptor Binding	RNA Binding Actin Binding Protein Binding Cadherin Binding Protein Kinase A Binding ATPase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Synaptic Transmission, Dopaminergic G Protein-coupled Receptor Internalization Cellular Calcium Ion Homeostasis Autophagy G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Learning Or Memory Learning Locomotory Behavior Positive Regulation Of Cell Population Proliferation Visual Learning Response To Xenobiotic Stimulus Regulation Of Dopamine Secretion Negative Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of Cytokinesis Circadian Regulation Of Gene Expression Response To Histamine Social Behavior Gastric Emptying Positive Regulation Of Renal Sodium Excretion Response To Cocaine Dopamine Metabolic Process Negative Regulation Of Apoptotic Process Regulation Of Potassium Ion Transport Response To Morphine Regulation Of Circadian Sleep/wake Cycle, Sleep Response To Ethanol Negative Regulation Of Blood Pressure Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Transcription By RNA Polymerase II Acid Secretion Behavioral Response To Cocaine Negative Regulation Of Oligodendrocyte Differentiation Arachidonic Acid Secretion Negative Regulation Of Protein Secretion Musculoskeletal Movement, Spinal Reflex Action Negative Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Synaptic Transmission, Glutamatergic Prepulse Inhibition Phospholipase C-activating Dopamine Receptor Signaling Pathway Positive Regulation Of Dopamine Receptor Signaling Pathway Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Locomotion Involved In Locomotory Behavior Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Negative Regulation Of Voltage-gated Calcium Channel Activity	Regulation Of Cell Shape Regulation Of Cell Size Positive Regulation Of Gene Expression Protein Kinase A Signaling Positive Regulation Of Cell Migration Regulation Of Actin Filament Bundle Assembly Regulation Of Rap Protein Signal Transduction Negative Regulation Of Homotypic Cell-cell Adhesion Negative Regulation Of GTPase Activity Cellular Response To Platelet-derived Growth Factor Stimulus Regulation Of GTPase Activity Apical Protein Localization Establishment Of Protein Localization Negative Regulation Of Cell Size Barbed-end Actin Filament Capping Establishment Of Endothelial Barrier Protein Localization To Plasma Membrane Cellular Response To Thyroid Hormone Stimulus Regulation Of Ruffle Assembly Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Organelle Assembly Positive Regulation Of Protein Localization To Early Endosome Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Adherens Junction Organization Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways		Dopamine receptors G alpha (i) signalling events	Recycling pathway of L1 Recycling pathway of L1 Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs		Ziprasidone Cabergoline Ropinirole Olanzapine Clozapine Sulpiride Loxapine Remoxipride Pramipexole Chlorpromazine Buspirone Haloperidol Amoxapine Lisuride Apomorphine Dopamine Ergoloid mesylate Pimozide Domperidone Pergolide Bromocriptine Quetiapine Levodopa Aripiprazole Chlorprothixene Paliperidone Yohimbine Methotrimeprazine Iloperidone Rotigotine ACP-104 Cariprazine Mianserin Asenapine Amisulpride Sarizotan Sumanirole Captodiame AS-8112 Blonanserin Pipamperone Tianeptine Dihydro-alpha-ergocryptine Epicriptine Pardoprunox Piribedil Tiapride Dihydroergocristine Aripiprazole lauroxil	1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS		Chronotype ( 30696823) Feeling hurt ( 29500382) Personality dimensions ( 23903073) Smooth-surface caries ( 24556642)	Cognitive function ( 24684796) Computer vision syndrome ( 33941792) Coronary artery disease ( 32469254) Multiple sclerosis ( 31604244)
Interacting Genes		20 interacting genes: CLIC6 DRD1 EEF1B2 EEF1G EPB41 EPB41L1 EPB41L2 FLNA GIPC1 GNAI1 GRB2 GSK3B MPDZ NCK1 NCS1 POLE2 RDX RGS9 SPTSSB USP48	22 interacting genes: ABCC2 ARHGDIA C1QTNF9 CALM1 CPNE1 CPNE2 CPNE4 DRD3 EZR GNA13 ICAM2 ITGB2 KMT2A L1CAM LINC01554 PSME3 ROCK1 SLC9A3R1 SLC9A3R2 TSC1 VPS11 VWA5A
Entrez ID		1814	5962
HPRD ID		00540	01534
Ensembl ID		ENSG00000151577	ENSG00000137710
Uniprot IDs		A1A4V4 A8K8E4 E9PCM4 P35462 X5D2G4	B0YJ88 P35241 Q6PKD3
PDB IDs		3PBL
Enriched GO Terms of Interacting Partners?
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