CTNNAL1 and RNF135

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		CTNNAL1	RNF135
Description		catenin alpha like 1	ring finger protein 135
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane	Cytoplasm Cytosol Cytoplasmic Stress Granule Ribonucleoprotein Complex
	Molecular Function	Protein Binding Cadherin Binding Actin Filament Binding	Ubiquitin-protein Transferase Activity Protein Binding RIG-I Binding Identical Protein Binding Ribonucleoprotein Complex Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cell Adhesion Rho Protein Signal Transduction	Protein Polyubiquitination Free Ubiquitin Chain Polymerization Protein Ubiquitination Positive Regulation Of Interferon-beta Production RIG-I Signaling Pathway Innate Immune Response Regulation Of Innate Immune Response Protein Homooligomerization Protein K63-linked Ubiquitination Antiviral Innate Immune Response
Pathways			DDX58/IFIH1-mediated induction of interferon-alpha/beta Ovarian tumor domain proteases TRAF3-dependent IRF activation pathway TRAF6 mediated IRF7 activation TRAF6 mediated NF-kB activation TRAF6 mediated NF-kB activation NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 Negative regulators of DDX58/IFIH1 signaling Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS			Height ( 18391951) Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		12 interacting genes: AKAP13 BRME1 CALU DMD NEK1 PCGF2 RNF135 SERTAD3 TRIM7 TSC22D4 USH1C ZBED1	10 interacting genes: CTBP2 CTNNAL1 DDX58 ENOX2 GOLGA2 HSF2BP IFIH1 TEPSIN UBE2D2 UBE2N
Entrez ID		8727	84282
HPRD ID		09210	11506
Ensembl ID		ENSG00000119326	ENSG00000181481
Uniprot IDs		B3KMX6 Q9UBT7	B3KV69 Q8IUD6
PDB IDs			7JL1 7JL3
Enriched GO Terms of Interacting Partners?
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