CTNNAL1 and AKAP13

Number of citations of the paper that reports this interaction (PubMedID 12270917)
24

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (in vivo, in vitro, two hybrid)

		CTNNAL1	AKAP13
Description		catenin alpha like 1	A-kinase anchoring protein 13
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane	Nucleus Cytosol Cell Cortex Actin Cytoskeleton Membrane Cortical Actin Cytoskeleton Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Cadherin Binding Actin Filament Binding	CAMP-dependent Protein Kinase Activity MAP-kinase Scaffold Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding Metal Ion Binding Protein Kinase A Binding Molecular Adaptor Activity
	Biological Process	Cell Adhesion Rho Protein Signal Transduction	Protein Phosphorylation G Protein-coupled Receptor Signaling Pathway Heart Development Regulation Of Rho Protein Signal Transduction Positive Regulation Of Rho Protein Signal Transduction Intracellular Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAP Kinase Activity Regulation Of Small GTPase Mediated Signal Transduction Nuclear Export Cardiac Muscle Cell Differentiation Regulation Of Sarcomere Organization Bone Development Cell Growth Involved In Cardiac Muscle Cell Development Adrenergic Receptor Signaling Pathway Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process
Pathways			NRAGE signals death through JNK G alpha (12/13) signalling events RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle
Drugs
Diseases
GWAS			Birth weight ( 31043758) Body shape index ( 34021172) Central corneal thickness ( 32528159 31798171 29760442 20719862) Corneal structure ( 23291589) Coronary artery disease ( 29212778) Granulocyte percentage of myeloid white cells ( 27863252) Hemoglobin ( 32888494) High myopia ( 32428537) Idiopathic pulmonary fibrosis ( 31710517 29066090) Immature fraction of reticulocytes ( 32888494) Intraocular pressure ( 29617998) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Medication use (diuretics) ( 31015401) Metabolite levels ( 23823483) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244) Neutrophil percentage of white cells ( 32888494) Offspring birth weight ( 31043758) Platelet count ( 32888494) Platelet distribution width ( 32888494) Post-bronchodilator lung function in asthma (FEV1/FVC) ( 32989782) Psoriasis ( 25939698) Pulse pressure ( 30578418) Red blood cell count ( 32888494) Refractive error ( 32231278) Response to platinum-based chemotherapy (carboplatin) ( 21844884) Systolic blood pressure ( 30578418) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		12 interacting genes: AKAP13 BRME1 CALU DMD NEK1 PCGF2 RNF135 SERTAD3 TRIM7 TSC22D4 USH1C ZBED1	21 interacting genes: APP CTNNAL1 ESR1 ESR2 GNA12 GNAQ LINC00839 MAP1LC3A PPARA PRKAR2A PRKD1 RANBP2 RHOA RTKN RXRB SRPK2 THRA YWHAB YWHAE YWHAG YWHAZ
Entrez ID		8727	11214
HPRD ID		09210	05253
Ensembl ID		ENSG00000119326	ENSG00000170776
Uniprot IDs		B3KMX6 Q9UBT7	A8MYJ1 B0AZU4 Q12802
PDB IDs			2DRN 2LG1 4D0N 4D0O 6BCA
Enriched GO Terms of Interacting Partners?
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