SERPINB7 and OGDH

		SERPINB7	OGDH
Description		serpin family B member 7	oxoglutarate dehydrogenase
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Nucleus Mitochondrion Mitochondrial Matrix Mitochondrial Membrane Oxoglutarate Dehydrogenase Complex
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity	Oxoglutarate Dehydrogenase (succinyl-transferring) Activity Protein Binding Thiamine Pyrophosphate Binding Heat Shock Protein Binding Oxoglutarate Dehydrogenase (NAD+) Activity Metal Ion Binding Chaperone Binding
	Biological Process	Negative Regulation Of Endopeptidase Activity Positive Regulation Of Transforming Growth Factor Beta1 Production Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of Glomerular Mesangial Cell Proliferation Positive Regulation Of Platelet-derived Growth Factor Production	Generation Of Precursor Metabolites And Energy Glycolytic Process Tricarboxylic Acid Cycle 2-oxoglutarate Metabolic Process Succinyl-CoA Metabolic Process NADH Metabolic Process Cerebellar Cortex Development Striatum Development Hippocampus Development Thalamus Development Pyramidal Neuron Development Tangential Migration From The Subventricular Zone To The Olfactory Bulb Olfactory Bulb Mitral Cell Layer Development Histone Succinylation
Pathways			Glyoxylate metabolism and glycine degradation Lysine catabolism Citric acid cycle (TCA cycle)
Drugs			NADH Valproic acid Xanthinol
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 31361310 30929738 34103634 32296059 31619474) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Food allergy ( 29051540) Hen's egg allergy ( 29051540) Systolic blood pressure ( 29208002)	Low density lipoprotein cholesterol levels ( 32154731) Lung cancer in never smokers ( 28604730) Systolic blood pressure change trajectory ( 27980656)
Interacting Genes		10 interacting genes: FBXO22 HRH4 OGDH PHLPP1 PIGN RELCH RNF152 SLC5A2 TAX1BP1 ZCCHC2	6 interacting genes: ANXA2 DLD DLST HSD17B10 PLSCR1 SERPINB7
Entrez ID		8710	4967
HPRD ID		04524	08938
Ensembl ID		ENSG00000166396	ENSG00000105953
Uniprot IDs		A8K3Q8 O75635	A0A140VJQ5 B4E3E9 E9PCR7 Q02218
PDB IDs			3ERY
Enriched GO Terms of Interacting Partners?
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