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OGDH

Description oxoglutarate dehydrogenase
Image
GO Annotations Cellular Component
  • Nucleus
  • Mitochondrion
  • Mitochondrial Matrix
  • Mitochondrial Membrane
  • Oxoglutarate Dehydrogenase Complex
Molecular Function
  • Oxoglutarate Dehydrogenase (succinyl-transferring) Activity
  • Protein Binding
  • Thiamine Pyrophosphate Binding
  • Heat Shock Protein Binding
  • Oxoglutarate Dehydrogenase (NAD+) Activity
  • Metal Ion Binding
  • Chaperone Binding
Biological Process
  • Generation Of Precursor Metabolites And Energy
  • Glycolytic Process
  • Tricarboxylic Acid Cycle
  • 2-oxoglutarate Metabolic Process
  • Succinyl-CoA Metabolic Process
  • NADH Metabolic Process
  • Cerebellar Cortex Development
  • Striatum Development
  • Hippocampus Development
  • Thalamus Development
  • Pyramidal Neuron Development
  • Tangential Migration From The Subventricular Zone To The Olfactory Bulb
  • Olfactory Bulb Mitral Cell Layer Development
  • Histone Succinylation
Pathways
  • Glyoxylate metabolism and glycine degradation
  • Lysine catabolism
  • Citric acid cycle (TCA cycle)
Drugs
  • NADH
  • Valproic acid
  • Xanthinol
Diseases
GWAS
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Lung cancer in never smokers ( 28604730)
  • Systolic blood pressure change trajectory ( 27980656)
Interacting Genes 6 interacting genes: ANXA2 DLD DLST HSD17B10 PLSCR1 SERPINB7
Entrez ID 4967
HPRD ID 08938
Ensembl ID ENSG00000105953
Uniprot IDs A0A140VJQ5 B4E3E9 E9PCR7 Q02218
PDB IDs 3ERY
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025