B4GALT4 and TIGIT

		B4GALT4	TIGIT
Description		beta-1,4-galactosyltransferase 4	T cell immunoreceptor with Ig and ITIM domains
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane Golgi Cisterna Membrane	Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	N-acetyllactosamine Synthase Activity Galactosyltransferase Activity Metal Ion Binding	Signaling Receptor Binding Protein Binding Identical Protein Binding
	Biological Process	Carbohydrate Metabolic Process Protein Glycosylation Membrane Lipid Metabolic Process Glycosylation	Negative Regulation Of Interleukin-12 Production Positive Regulation Of Interleukin-10 Production Negative Regulation Of T Cell Activation
Pathways		Keratan sulfate biosynthesis N-Glycan antennae elongation
Drugs		N-Acetylglucosamine
Diseases
GWAS		Clozapine-induced cytotoxicity ( 25656473) First year height change in growth hormone-treated short stature ( 32652002) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Survival in pancreatic cancer ( 28470677)
Interacting Genes		2 interacting genes: POLE4 TIGIT	11 interacting genes: B4GALT4 CCDC191 GRAMD1C MAL NECTIN2 NECTIN3 NECTIN4 PLLP PVR QTRT2 ZDHHC23
Entrez ID		8702	201633
HPRD ID		04930	08804
Ensembl ID		ENSG00000121578	ENSG00000181847
Uniprot IDs		B2RAZ5 B3KM35 O60513	Q495A1
PDB IDs			3Q0H 3RQ3 3UCR 3UDW 5V52
Enriched GO Terms of Interacting Partners?
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