TIGIT and B4GALT4

		TIGIT	B4GALT4
Description		T cell immunoreceptor with Ig and ITIM domains	beta-1,4-galactosyltransferase 4
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Golgi Membrane Golgi Apparatus Integral Component Of Membrane Golgi Cisterna Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Identical Protein Binding	N-acetyllactosamine Synthase Activity Galactosyltransferase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Interleukin-12 Production Positive Regulation Of Interleukin-10 Production Negative Regulation Of T Cell Activation	Carbohydrate Metabolic Process Protein Glycosylation Membrane Lipid Metabolic Process Glycosylation
Pathways			Keratan sulfate biosynthesis N-Glycan antennae elongation
Drugs			N-Acetylglucosamine
Diseases
GWAS			Clozapine-induced cytotoxicity ( 25656473) First year height change in growth hormone-treated short stature ( 32652002) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Survival in pancreatic cancer ( 28470677)
Interacting Genes		11 interacting genes: B4GALT4 CCDC191 GRAMD1C MAL NECTIN2 NECTIN3 NECTIN4 PLLP PVR QTRT2 ZDHHC23	2 interacting genes: POLE4 TIGIT
Entrez ID		201633	8702
HPRD ID		08804	04930
Ensembl ID		ENSG00000181847	ENSG00000121578
Uniprot IDs		Q495A1	B2RAZ5 B3KM35 O60513
PDB IDs		3Q0H 3RQ3 3UCR 3UDW 5V52
Enriched GO Terms of Interacting Partners?
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