NPFF and NPFFR1

Number of citations of the paper that reports this interaction (PubMedID 11024015)
69

Data Source:
HPRD (in vitro, in vivo)

		NPFF	NPFFR1
Description		neuropeptide FF-amide peptide precursor	neuropeptide FF receptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Dendrite Perikaryon Axon Terminus Postsynapse	Plasma Membrane Integral Component Of Plasma Membrane Cilium
	Molecular Function	G Protein-coupled Receptor Binding Signaling Receptor Binding Neuropeptide Hormone Activity	G Protein-coupled Receptor Activity Protein Binding Neuropeptide Receptor Activity Peptide Binding
	Biological Process	Neuropeptide Signaling Pathway Chemical Synaptic Transmission Excitatory Postsynaptic Potential	G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Biological_process
Pathways		Orexin and neuropeptides FF and QRFP bind to their respective receptors G alpha (q) signalling events	Orexin and neuropeptides FF and QRFP bind to their respective receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Acute lymphoblastic leukemia (childhood) ( 23007406) Blood protein levels ( 28240269) Body size at age 10 ( 32376654) Cognitive decline rate in late mild cognitive impairment ( 26252872) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		4 interacting genes: NPFFR1 NPFFR2 NPY ZDHHC17	2 interacting genes: NPFF TCP11
Entrez ID		8620	64106
HPRD ID		06869	12120
Ensembl ID		ENSG00000139574	ENSG00000148734
Uniprot IDs		O15130	Q9GZQ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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