NPFFR1 and TCP11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NPFFR1	TCP11
Description		neuropeptide FF receptor 1	t-complex 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cilium	Acrosomal Vesicle Integral Component Of Membrane Sperm Flagellum Sperm Midpiece
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Neuropeptide Receptor Activity Peptide Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Biological_process	Signal Transduction Multicellular Organism Development Spermatogenesis Protein Kinase A Signaling Cell Differentiation Regulation Of CAMP-mediated Signaling Regulation Of Sperm Capacitation
Pathways		Orexin and neuropeptides FF and QRFP bind to their respective receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 23007406) Blood protein levels ( 28240269) Body size at age 10 ( 32376654) Cognitive decline rate in late mild cognitive impairment ( 26252872) Squamous cell lung carcinoma ( 28604730)	Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) HDL cholesterol levels ( 32203549) Height ( 28552196 18391951) Hip circumference adjusted for BMI ( 34021172) Liver enzyme levels (alkaline phosphatase) ( 33972514) Subcortical volume (MOSTest) ( 32665545) Systemic lupus erythematosus ( 28714469)
Interacting Genes		2 interacting genes: NPFF TCP11	13 interacting genes: AIMP2 APP FANCF GRAPL GSTZ1 IKBKG KRTAP13-3 LMBRD1 MAP2K1 MED28 NPFFR1 VAV2 ZNF688
Entrez ID		64106	6954
HPRD ID		12120	01749
Ensembl ID		ENSG00000148734	ENSG00000124678
Uniprot IDs		Q9GZQ6	B7ZAT8 Q8WWU5
PDB IDs
Enriched GO Terms of Interacting Partners?
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