STC2 and ADAM11

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		STC2	ADAM11
Description		stanniocalcin 2	ADAM metallopeptidase domain 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Perinuclear Region Of Cytoplasm	Plasma Membrane Integral Component Of Membrane Collagen-containing Extracellular Matrix
	Molecular Function	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity	Metalloendopeptidase Activity Integrin Binding Metallopeptidase Activity
	Biological Process	Cellular Calcium Ion Homeostasis Signal Transduction Embryo Implantation Negative Regulation Of Gene Expression Response To Vitamin D Response To Peptide Hormone Decidualization Regulation Of Hormone Biosynthetic Process Cellular Response To Hypoxia	Proteolysis Integrin-mediated Signaling Pathway
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	LGI-ADAM interactions
Drugs
Diseases
GWAS		Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Appendicular lean mass ( 33097823) Atrial fibrillation ( 29892015) Birth weight ( 31043758) Body shape index ( 34021172) Height ( 25429064 31562340) Hip circumference adjusted for BMI ( 34021172) Immunoglobulin A vasculitis ( 28698626) Prostate cancer ( 23535732) Retinitis pigmentosa ( 33514863) Urate levels in overweight individuals ( 25811787) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		20 interacting genes: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 CELF6 CPN1 EIF2B3 ELOB ERGIC1 FAF2 FGFR4 HK3 PEBP1 PLA2G5 POLR2C POLR3F PPP1R8 PTN RNF44	1 interacting genes: STC2
Entrez ID		8614	4185
HPRD ID		04717	01114
Ensembl ID		ENSG00000113739	ENSG00000073670
Uniprot IDs		O76061 Q6FHC9	B4DKD2 O75078
PDB IDs
Enriched GO Terms of Interacting Partners?
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