CDC14B and SPANXN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CDC14B	SPANXN2
Description		cell division cycle 14B	SPANX family member N2
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Mitotic Spindle
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization DNA Repair Protein Dephosphorylation Mitotic G2 DNA Damage Checkpoint Signaling Regulation Of Exit From Mitosis Positive Regulation Of Cytokinesis Peptidyl-tyrosine Dephosphorylation Cilium Assembly Positive Regulation Of Ubiquitin Protein Ligase Activity
Pathways		MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS		Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Household income ( 31844048) Intelligence (MTAG) ( 29326435) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		20 interacting genes: BCL10 BUB1 CCND1 CDKN2A DLC1 MCC MFAP1 MLH3 MSH2 MTDH MYCBP2 PRKAB2 PSMB1 SIRT2 SKP2 SMAD4 SPANXN2 STK11 TP53 ZNF696	51 interacting genes: ANKRD1 ANKRD11 BANP BEND7 BHLHB9 BIVM CAVIN1 CDC14B CDCA8 CDYL2 COIL DPPA4 EPB41L3 FAM193B FAM204A H2BC11 H2BC15 H2BC21 KHDC4 KRCC1 L3MBTL3 MEOX2 MTIF3 NOL12 NUMB PBX4 PICK1 RPL27 RRP1 SFMBT1 SMN1 SMN2 SNIP1 SNRPD2 SP3 SP4 SRP14 STAC3 SYTL4 THAP1 TNNI1 VAX1 YAF2 ZBTB48 ZNF19 ZNF2 ZNF438 ZNF526 ZNF655 ZNF75A ZNF84
Entrez ID		8555	494119
HPRD ID		04615	18091
Ensembl ID		ENSG00000081377	ENSG00000268988
Uniprot IDs		O60729	Q5MJ10
PDB IDs		1OHC 1OHD 1OHE
Enriched GO Terms of Interacting Partners?
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