CDC14B and MLH3

Number of citations of the paper that reports this interaction (PubMedID 24412244)
2

Data Source:
BioGRID (two hybrid)

		CDC14B	MLH3
Description		cell division cycle 14B	mutL homolog 3
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Mitotic Spindle	Synaptonemal Complex Male Germ Cell Nucleus Nucleus Nucleoplasm Chiasma Mismatch Repair Complex
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Chromatin Binding Satellite DNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity Centromeric DNA Binding Mismatched DNA Binding
	Biological Process	Microtubule Cytoskeleton Organization DNA Repair Protein Dephosphorylation Mitotic G2 DNA Damage Checkpoint Signaling Regulation Of Exit From Mitosis Positive Regulation Of Cytokinesis Peptidyl-tyrosine Dephosphorylation Cilium Assembly Positive Regulation Of Ubiquitin Protein Ligase Activity	Mismatch Repair Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiotic Nuclear Division Female Meiosis I Protein Localization
Pathways		MAPK6/MAPK4 signaling	Meiotic recombination
Drugs
Diseases
GWAS		Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Household income ( 31844048) Intelligence (MTAG) ( 29326435) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Waist circumference adjusted for body mass index ( 34021172)	Inflammatory bowel disease ( 23128233) Mood instability ( 29187730) Refractive error ( 32231278)
Interacting Genes		20 interacting genes: BCL10 BUB1 CCND1 CDKN2A DLC1 MCC MFAP1 MLH3 MSH2 MTDH MYCBP2 PRKAB2 PSMB1 SIRT2 SKP2 SMAD4 SPANXN2 STK11 TP53 ZNF696	48 interacting genes: AKT1 ALDOB ANP32B AOPEP AR BAAT CCDC180 CDC14B CDK8 CTSV CYLC2 DVL1 EXO1 FANCC FBP1 FBP2 FRAT2 GALNT12 HEMGN HRAS HSD17B3 IGFBP3 LEF1 MAP2K1 MLH1 MSANTD3 MSH4 MSH5 NANS PCNA PPP2CB PPP3R2 RASA1 SEC61B SFRP2 SMAD1 STX17 TBC1D2 TDRD7 TGFB1 TMEFF1 TMOD1 TRIM55 TRIM63 TSTD2 XPA ZDHHC17 ZNF510
Entrez ID		8555	27030
HPRD ID		04615	05094
Ensembl ID		ENSG00000081377	ENSG00000119684
Uniprot IDs		O60729	Q2M1Z1 Q9UHC1
PDB IDs		1OHC 1OHD 1OHE
Enriched GO Terms of Interacting Partners?
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