CIPC and RABGEF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		CIPC	RABGEF1
Description		CLOCK interacting pacemaker	RAB guanine nucleotide exchange factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol	Nucleolus Early Endosome Cytosol Early Endosome Membrane Recycling Endosome
	Molecular Function	Protein Binding	DNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Small GTPase Binding
	Biological Process	Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process	Protein Targeting To Membrane Endocytosis Regulation Of Catalytic Activity
Pathways			TBC/RABGAPs RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Aspartate aminotransferase levels ( 33547301) Intake of total sugars ( 31005972)	Aortic root size ( 21223598) Central corneal thickness ( 32528159 29760442)
Interacting Genes		8 interacting genes: APPL1 CSNK2B DELEC1 DNAL1 NCK2 RABGEF1 RORC RPS6KL1	50 interacting genes: ABI2 ANKRD29 AP1G1 ARRDC3 BLOC1S6 CCHCR1 CDC37 CIPC DAZAP2 DCTN2 DGCR6 DNAJC5 EMILIN1 GGA1 GGA2 GPRASP2 HOOK2 HRAS IHO1 KXD1 MID2 MON1A MON1B OIP5 RAB33B RAB4A RABEP1 RAD23A RASAL3 RNF11 RNF168 RPS27A SESTD1 SNAPIN SPART SSX3 TCHP TEAD4 THOC1 TRIM15 TRIM54 TXN2 UBA52 UBB UBC UBE2D1 UBE2D3 WASHC1 YWHAB ZC2HC1C
Entrez ID		85457	27342
HPRD ID		13890	11477
Ensembl ID		ENSG00000198894	ENSG00000154710
Uniprot IDs		Q9C0C6	A0A024RDL6 A8K3R3 B3KMF1 Q9UJ41
PDB IDs			1TXU 2C7M 2C7N 2OT3 4N3X 4N3Y 4N3Z 4Q9U
Enriched GO Terms of Interacting Partners?
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