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TMEM60 and AQP2
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
86
Data Source:
BioGRID
(two hybrid)
TMEM60
AQP2
Description
transmembrane protein 60
aquaporin 2
Image
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Golgi Apparatus
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Transport Vesicle Membrane
Perinuclear Region Of Cytoplasm
Recycling Endosome
Extracellular Exosome
Lumenal Side Of Membrane
Molecular Function
Protein Binding
Water Transmembrane Transporter Activity
Protein Binding
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Biological Process
Renal Water Homeostasis
Renal Water Transport
Water Transport
Glycerol Transport
Cellular Response To Water Deprivation
Protein Homotetramerization
Transmembrane Transport
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Metanephric Collecting Duct Development
Pathways
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Drugs
Diseases
GWAS
Chronic kidney disease (
20383146
)
Estimated glomerular filtration rate (
31152163
31451708
30604766
)
Estimated glomerular filtration rate in non-diabetics (
31451708
)
Glomerular filtration rate (creatinine) (
28452372
26831199
)
Glomerular filtration rate in non diabetics (creatinine) (
26831199
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Allergic rhinitis (
30013184
)
Obsessive-compulsive disorder (
22889921
)
Interacting Genes
89 interacting genes:
AMIGO1
ANKS6
APOL2
AQP2
AQP6
ASGR2
BEST2
BIK
BSND
CD300A
CD53
CD74
CLDN7
CNR2
CPLX4
CYB5R3
EBP
EDA
ERGIC3
EVI2B
FAM209A
FFAR2
FNDC9
GJA8
GJB5
GJB6
GORAB
GPR152
GPR42
GPX8
HERPUD2
HIBADH
HSD17B13
IFNGR2
KCNK5
KIAA2013
LEUTX
LHFPL5
LMNA
LRRC3B
LRRC59
MFF
MGST3
MMD
MMGT1
PAGE1
PGRMC2
PI16
REEP2
REEP4
RETREG3
RHCG
RNASEK
SCN3B
SLC10A1
SLC10A6
SLC13A4
SLC16A2
SLC18A1
SLC23A2
SLC30A2
SLC30A4
SLC35E3
SLC38A1
SLC39A2
SLC4A1
SLC7A8
SPAG4
SPNS3
SSMEM1
STOM
STX1A
SYT1
THAP4
TLCD4
TMCO5A
TMED9
TMEM139
TMEM14B
TMEM203
TMEM237
TMEM45B
TMEM52B
TMEM86B
TMEM9
TMPPE
TMPRSS2
TTYH1
VMA21
61 interacting genes:
ACTB
BCAP31
C4orf3
CCDC167
CDIPT
CERT1
CLCA4
CLDN7
CREB3
CREB3L1
CTSA
CXCL16
EEF1A1
EFNA5
ELL2
ERG28
ERGIC3
ERMP1
FAM209A
GPAA1
GPX8
IER3
IGFBP5
INSIG2
LEUTX
LHFPL5
LMAN2L
MRM1
MS4A13
MUC1
NDFIP2
OLFM4
OR10AG1
PANX1
PDZK1IP1
PLP2
PNLIPRP1
RTP2
SLC26A6
SLC30A2
SLC38A7
SLC5A2
SNAP47
SNX5
SPCS1
SSR3
STUB1
STX8
SUPT20H
TM9SF2
TMEM109
TMEM218
TMEM230
TMEM236
TMEM60
TMEM86A
TMEM97
TRARG1
UBE2J1
VAPB
YIPF6
Entrez ID
85025
359
HPRD ID
12923
00141
Ensembl ID
ENSG00000135211
ENSG00000167580
Uniprot IDs
Q9H2L4
P41181
PDB IDs
4NEF
4OJ2
6QF5
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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