REPS1 and WWC2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		REPS1	WWC2
Description		RALBP1 associated Eps domain containing 1	WW and C2 domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit	Cytoplasm Cytosol
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding	Kinase Binding Molecular Adaptor Activity
	Biological Process	Endocytosis Receptor-mediated Endocytosis Endosomal Transport	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Cell Migration Regulation Of Hippo Signaling Negative Regulation Of Hippo Signaling Negative Regulation Of Organ Growth
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834) Type 2 diabetes ( 32499647)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Aspartate aminotransferase levels ( 33547301) Heel bone mineral density ( 30598549) Height ( 28552196 20881960) Initial alcohol sensitivity ( 30276832)
Interacting Genes		17 interacting genes: ANKRD1 ATF4 CRK FLNC GRB2 HSF1 ITSN2 MZT1 PIN1 RAB11FIP2 RALA RALB RALBP1 REPS2 TRAPPC2 TRAPPC2L WWC2	4 interacting genes: REPS1 WWC1 WWC3 YWHAQ
Entrez ID		85021	80014
HPRD ID		09687	12529
Ensembl ID		ENSG00000135597	ENSG00000151718
Uniprot IDs		B2R7D3 Q96D71	Q6AWC2
PDB IDs
Enriched GO Terms of Interacting Partners?
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