PPM1D and LYPD3

Number of citations of the paper that reports this interaction (PubMedID 25640309)
8

Data Source:
BioGRID (two hybrid)

		PPM1D	LYPD3
Description		protein phosphatase, Mg2+/Mn2+ dependent 1D	LY6/PLAUR domain containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Anchored Component Of Plasma Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Mitogen-activated Protein Kinase Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Laminin Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle DNA Methylation Protein Phosphorylation Protein Dephosphorylation Negative Regulation Of Cell Population Proliferation Cellular Response To Starvation Response To Radiation Response To Bacterium DNA Damage Response, Signal Transduction By P53 Class Mediator Peptidyl-threonine Dephosphorylation Negative Regulation Of Gene Expression, Epigenetic Regulation Of Transcription Initiation From RNA Polymerase II Promoter	Cell-matrix Adhesion
Pathways		Transcriptional regulation by RUNX2	Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163)	Cotinine glucuronidation ( 25293881)
Interacting Genes		25 interacting genes: ATP6V1A BEX2 CASZ1 CHEK2 DIRAS3 DKK3 EPSTI1 ERRFI1 GLCE H3-3A H3C1 ITIH5 KDM1A LYPD3 MAPK11 MDM2 MRC2 NAT2 NCL NSD3 OSGIN1 RHOBTB2 RPL5 TP53 UBC	18 interacting genes: AGR2 AGR3 ATP1A3 AURKA BAG4 BRMS1 CASP8 CHEK2 CTRB1 ERBB2 IGF1R LSP1 PALB2 PPM1D PTPRJ RB1CC1 SMAD4 STK11
Entrez ID		8493	27076
HPRD ID		05482	10783
Ensembl ID		ENSG00000170836	ENSG00000124466
Uniprot IDs		A0A0S2Z4M2 O15297	B2RBR3 O95274
PDB IDs			6IOM 6ION
Enriched GO Terms of Interacting Partners?
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