BUD13 and GPKOW

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid, two hybrid, two hybrid, affinity chromatography technology)

		BUD13	GPKOW
Description		BUD13 homolog	G-patch domain and KOW motifs
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U2-type Spliceosomal Complex RES Complex U2-type Precatalytic Spliceosome	Nucleus Nucleoplasm Spliceosomal Complex
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Alcohol consumption (drinks per week) ( 30643258) Apolipoprotein A1 levels ( 32203549) Body mass index ( 31978080) Bone mineral density (femoral neck) in inflammatory bowel disease ( 29603369) Cardiovascular risk factors (age interaction) ( 20838585) Coronary artery disease ( 29263402 29212778) Cutaneous squamous cell carcinoma ( 27424798 32041948) Delirium ( 29631748) Disease progression in age-related macular degeneration ( 29346644) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) General risk tolerance (MTAG) ( 30643258) HDL Cholesterol - Triglycerides (HDLC-TG) ( 21386085) HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HIV-1 susceptibility ( 21160409) Hypertriglyceridemia ( 31087446 23505323) LDL cholesterol ( 20864672) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Lipid traits ( 24023261) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Low density lipoprotein cholesterol levels ( 33339817) Lung cancer ( 28604730) Manganese levels ( 26025379) Metabolic syndrome ( 30382898 21386085) Metabolic syndrome (bivariate traits) ( 21386085) Metabolite levels ( 23823483 31628463) Platelet count ( 32888494 27863252) Post bronchodilator FEV1/FVC ratio ( 26634245) Pulse pressure ( 30224653) Red cell distribution width ( 28957414) Response to Vitamin E supplementation ( 22437554) Severe influenza A (H1N1) infection ( 26379185) Sum eosinophil basophil counts ( 27863252) Total cholesterol levels ( 33339817) Triglyceride levels ( 32203549 32902719 26763881 30911093 28371326 29615537 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglycerides ( 21909109 18193044 20864672 26160806 24886709) Triglycerides-Blood Pressure (TG-BP) ( 21386085) Vitamin E levels ( 21729881) Waist Circumference - Triglycerides (WC-TG) ( 21386085)
Interacting Genes		4 interacting genes: GPKOW NLRX1 RBMX2 SRPK2	48 interacting genes: APP ARMCX1 BUD13 CCDC57 CNKSR3 DDIT4L EFHC2 FBXO7 GMPPA GOLGA2 GSTM5 HOOK2 HSF2BP IKBKG KANK2 LNX1 LRP2BP LZTS1 MAD1L1 MEOX2 MESD MID2 MTUS2 NINL OGT PHF1 PIBF1 PICK1 POLR2G PPP1CA PRKAR1B PRPF4 PRPF8 REL ROPN1 SH3GL1 SORBS3 SPDYE4 TCEA1 TCEA2 TRAF2 TRIM23 TRIM27 VPS52 WDR77 WDR83 ZMYND12 ZRANB1
Entrez ID		84811	27238
HPRD ID		11307	06737
Ensembl ID		ENSG00000137656	ENSG00000068394
Uniprot IDs		Q9BRD0	Q92917
PDB IDs		5Z56 5Z57 5Z58 6FF4 6FF7 7ABI
Enriched GO Terms of Interacting Partners?
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