CRACR2A and SORBS3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CRACR2A	SORBS3
Description		calcium release activated channel regulator 2A	sorbin and SH3 domain containing 3
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GO Annotations	Cellular Component	Golgi Membrane Immunological Synapse Extracellular Region Cytoplasm Microtubule Organizing Center Cytoskeleton Plasma Membrane Membrane Trans-Golgi Network Membrane Weibel-Palade Body Specific Granule Lumen	Nucleus Cytosol Cytoskeleton Focal Adhesion
	Molecular Function	GTPase Activity Calcium Ion Binding Protein Binding GTP Binding	Structural Constituent Of Cytoskeleton Protein Binding Vinculin Binding
	Biological Process	Store-operated Calcium Entry Adaptive Immune Response Activation Of Store-operated Calcium Channel Activity T-helper 1 Cell Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of Calcium Ion Transport	Negative Regulation Of Transcription By RNA Polymerase II Actin Filament Organization Cell Adhesion Cell-substrate Adhesion Positive Regulation Of MAPK Cascade Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Stress Fiber Assembly
Pathways		Neutrophil degranulation	Smooth Muscle Contraction
Drugs
Diseases
GWAS			Diastolic blood pressure ( 30224653) HIV-1 viral setpoint ( 20205591) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Parkinson's disease ( 28892059)
Interacting Genes		35 interacting genes: ANKRD29 ASB3 ATN1 CCHCR1 CDC23 DDIT3 FAM156A FAM156B FAM86C1P FKBP6 GIGYF1 GOLGA2 KRT31 KRT75 KRTAP13-1 KRTAP19-5 LRIF1 MDFI MID2 MKRN3 NOTCH2NLA OIP5 PNMA5 POLR1C RBAK RORB SLAIN1 SORBS3 TLE5 TRAF1 TRIM29 USP2 ZC2HC1C ZNF20 ZNF655	137 interacting genes: ABI2 ABL1 ADAM15 ADAMTSL4 ADAT3 AKIRIN2 AKT2 ANKS1A ARNT2 C1orf109 CATSPER1 CBFA2T2 CBLB CCDC102B CCDC120 CCDC187 CCDC57 CCDC6 CCHCR1 CCNH CCNL1 CDC23 CDKN2C CFAP206 CHERP COG4 CPEB2 CPNE1 CPNE2 CPNE8 CPSF7 CRACR2A DDX17 DDX6 DIP2A DLG5 DMRTB1 DVL2 DVL3 EFHC1 EFS EIF3H ENKD1 FAM214B FAM53C FASLG FBXL19 FLOT1 FNDC11 FXR1 GAS8 GEM GLRA1 GPANK1 GPKOW GYS1 HGS HNRNPF HNRNPK HNRNPUL1 IMP3 INPPL1 INSC IQUB KANK2 KIAA0408 KIAA1217 KIFC3 MAPK1 MAPK3 MKRN3 MYO15B NAB2 NAF1 NCK1 NCKIPSD NEK6 NFKBID NHSL2 NOTCH3 NRBP1 OIP5 OSGIN1 PAK2 PAK5 PHETA1 PHF1 PIBF1 PLEKHN1 PLOD3 PNMA5 POLE2 POLR1C PPFIA3 PPIL6 PPP1R18 PPP3CC QARS1 RAD51D RBMX RIN1 ROPN1 RUNX1T1 SAFB2 SAXO1 SCNM1 SETD5 SH2D4A SHANK3 SOCS7 SPG21 SRCIN1 SYNPO2L TBC1D22B TCEANC TEAD4 TEPSIN TNS2 TRIM23 TRIM27 TRIM41 TSC1 TSGA10 TSGA10IP TXLNA USP2 VARS2 VCL VPS37B VPS37C WIPF2 ZBED1 ZBTB25 ZBTB7B ZC2HC1C ZC4H2 ZNF414
Entrez ID		84766	10174
HPRD ID		10079	11535
Ensembl ID		ENSG00000130038	ENSG00000120896
Uniprot IDs		Q9BSW2	O60504
PDB IDs		6PSD	2CT3 2DLM 2NWM 2YUP
Enriched GO Terms of Interacting Partners?
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