SMARCA5 and CHRAC1

Number of citations of the paper that reports this interaction (PubMedID 12434153)
115

Data Source:
HPRD (in vivo)

		SMARCA5	CHRAC1
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	chromatin accessibility complex subunit 1
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Fibrillar Center Nucleus Nucleoplasm Chromatin Silencing Complex Cytosol NURF Complex RSF Complex Intracellular Membrane-bounded Organelle Nuclear Replication Fork	Nucleus Epsilon DNA Polymerase Complex CHRAC
	Molecular Function	DNA Binding Helicase Activity Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA Hydrolase Activity ATP Hydrolysis Activity Nucleosome Binding Histone Binding ATP-dependent Chromatin Remodeler Activity	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	RDNA Heterochromatin Assembly Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Nucleosome Positioning Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Leukemia Inhibitory Factor	Chromatin Remodeling DNA Biosynthetic Process
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Deposition of new CENPA-containing nucleosomes at the centromere
Drugs		Beta-D-Glucose 4-Deoxy-Alpha-D-Glucose
Diseases
GWAS		Height ( 31562340) Malaria ( 31844061)	Experiencing mood swings ( 29500382)
Interacting Genes		19 interacting genes: BAZ1A BAZ1B BAZ2A CDT1 CHRAC1 CREB1 CTNNB1 DNMT3B GSK3A H3-3A H3C1 H4-16 HDAC2 MAF POLE3 PTEN RAD21 RSF1 SATB1	5 interacting genes: APP BAZ1A FAM9B POLE3 SMARCA5
Entrez ID		8467	54108
HPRD ID		04538	06275
Ensembl ID		ENSG00000153147	ENSG00000104472
Uniprot IDs		O60264	Q9NRG0
PDB IDs		6NE3
Enriched GO Terms of Interacting Partners?
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