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DCTN5 and EARS2

DCTN5

EARS2

Description dynactin subunit 5 glutamyl-tRNA synthetase 2, mitochondrial
Image No pdb structure
GO Annotations Cellular Component
  • Kinetochore
  • Nucleoplasm
  • Centrosome
  • Cytosol
  • Nuclear Membrane
  • Mitochondrion
  • Mitochondrial Matrix
Molecular Function
  • Protein Binding
  • TRNA Binding
  • Glutamate-tRNA Ligase Activity
  • ATP Binding
  • Zinc Ion Binding
  • Glutamate-tRNA(Gln) Ligase Activity
Biological Process
  • Ventricular Septum Development
  • Aorta Development
  • Coronary Vasculature Development
  • Glutamyl-tRNA Aminoacylation
  • TRNA Aminoacylation For Mitochondrial Protein Translation
Pathways
  • MHC class II antigen presentation
  • HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
  • COPI-mediated anterograde transport
  • COPI-independent Golgi-to-ER retrograde traffic
  • Mitochondrial tRNA aminoacylation
Drugs
  • Glutamic acid
Diseases
GWAS
  • Bipolar disorder ( 17554300)
Interacting Genes 10 interacting genes: C16orf82 CHP2 COG7 DYNLL1 EARS2 FATE1 KDM8 NINL PMEPA1 RBPMS 2 interacting genes: DCTN5 OGT
Entrez ID 84516 124454
HPRD ID 14551 11174
Ensembl ID ENSG00000166847 ENSG00000103356
Uniprot IDs Q9BTE1 Q5JPH6
PDB IDs 5NW4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?

© Madhavi K. Ganapathiraju 2012-2025