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EARS2 and DCTN5

EARS2

DCTN5

Description glutamyl-tRNA synthetase 2, mitochondrial dynactin subunit 5
Image No pdb structure
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Matrix
  • Kinetochore
  • Nucleoplasm
  • Centrosome
  • Cytosol
  • Nuclear Membrane
Molecular Function
  • TRNA Binding
  • Glutamate-tRNA Ligase Activity
  • ATP Binding
  • Zinc Ion Binding
  • Glutamate-tRNA(Gln) Ligase Activity
  • Protein Binding
Biological Process
  • Glutamyl-tRNA Aminoacylation
  • TRNA Aminoacylation For Mitochondrial Protein Translation
  • Ventricular Septum Development
  • Aorta Development
  • Coronary Vasculature Development
Pathways
  • Mitochondrial tRNA aminoacylation
  • MHC class II antigen presentation
  • HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
  • COPI-mediated anterograde transport
  • COPI-independent Golgi-to-ER retrograde traffic
Drugs
  • Glutamic acid
Diseases
GWAS
  • Bipolar disorder ( 17554300)
Interacting Genes 2 interacting genes: DCTN5 OGT 10 interacting genes: C16orf82 CHP2 COG7 DYNLL1 EARS2 FATE1 KDM8 NINL PMEPA1 RBPMS
Entrez ID 124454 84516
HPRD ID 11174 14551
Ensembl ID ENSG00000103356 ENSG00000166847
Uniprot IDs Q5JPH6 Q9BTE1
PDB IDs 5NW4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?

© Madhavi K. Ganapathiraju 2012-2025