ACBD6 and NMT2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ACBD6	NMT2
Description		acyl-CoA binding domain containing 6	N-myristoyltransferase 2
Image
GO Annotations	Cellular Component	Cytosol	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Extrinsic Component Of Membrane Host Cell
	Molecular Function	Fatty-acyl-CoA Binding Protein Binding Lipid Binding	Glycylpeptide N-tetradecanoyltransferase Activity Protein Binding
	Biological Process		N-terminal Peptidyl-glycine N-myristoylation Regulation Of Rhodopsin Mediated Signaling Pathway Intracellular Transport Of Virus
Pathways		Mitochondrial Fatty Acid Beta-Oxidation	Membrane binding and targetting of GAG proteins Inactivation, recovery and regulation of the phototransduction cascade
Drugs			Myristoyl-Coa S-(2-oxo)pentadecylcoa 1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL (Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE
Diseases
GWAS			Clozapine-induced agranulocytosis ( 25187353) Mild to moderate chronic kidney disease ( 31178898) Osteoporosis-related phenotypes (MTAG) ( 32107650) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		5 interacting genes: APP HSPB1 IKBKG NMT1 NMT2	14 interacting genes: ACBD6 ANXA4 ANXA7 APP BCL2 BTF3 CASP3 CSNK2B PPP1CC PRKCZ SMN1 TK1 TMED9 TP53
Entrez ID		84320	9397
HPRD ID		12416	11948
Ensembl ID		ENSG00000230124	ENSG00000152465
Uniprot IDs		A0A024R949 B2RAA8 Q9BR61	B3KT39 O60551 Q5VUC6
PDB IDs		2COP	4C2X 6PAU
Enriched GO Terms of Interacting Partners?
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