NMT2 and ANXA4

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		NMT2	ANXA4
Description		N-myristoyltransferase 2	annexin A4
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Extrinsic Component Of Membrane Host Cell	Nucleus Cytoplasm Plasma Membrane Cell Surface Vesicle Membrane Cytoplasmic Vesicle Nuclear Membrane Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Glycylpeptide N-tetradecanoyltransferase Activity Protein Binding	Phospholipase Inhibitor Activity Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Identical Protein Binding Calcium-dependent Protein Binding NF-kappaB Binding
	Biological Process	N-terminal Peptidyl-glycine N-myristoylation Regulation Of Rhodopsin Mediated Signaling Pathway Intracellular Transport Of Virus	Regulation Of Transcription By RNA Polymerase II Signal Transduction Notch Signaling Pathway Epithelial Cell Differentiation Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-8 Production Negative Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity
Pathways		Membrane binding and targetting of GAG proteins Inactivation, recovery and regulation of the phototransduction cascade
Drugs		Myristoyl-Coa S-(2-oxo)pentadecylcoa 1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL (Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE	Fluocinolone acetonide Copper
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Mild to moderate chronic kidney disease ( 31178898) Osteoporosis-related phenotypes (MTAG) ( 32107650) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Atrial fibrillation ( 28416818 30061737) Palmitoleic acid (16:1n-7) levels ( 23362303)
Interacting Genes		14 interacting genes: ACBD6 ANXA4 ANXA7 APP BCL2 BTF3 CASP3 CSNK2B PPP1CC PRKCZ SMN1 TK1 TMED9 TP53	8 interacting genes: GP2 NMT2 PADI4 POT1 RHOU SMPD1 TINF2 UCHL5
Entrez ID		9397	307
HPRD ID		11948	00112
Ensembl ID		ENSG00000152465	ENSG00000196975
Uniprot IDs		B3KT39 O60551 Q5VUC6	P09525 Q6LES2 Q6P452
PDB IDs		4C2X 6PAU	2ZOC
Enriched GO Terms of Interacting Partners?
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